And apparently Jay is "open" to coming back.

Excellent question. The only thing I’ve seen about CLR is the derision at Illumina’s attempt at calling it “not synthetic long reads”

I’m not sure which penny you think dropped or why you’ve quoted me in a way that I can’t directly reply to 🙄. Excluding instruments is weird and nonsensical. PacBio could drop instrument to $0 and charge more for reagents , but nothing would really change.

A dark hiring pattern at startups Giving employees equity but leaving out critical information that helps them value what it's actually worth I frequently see offers that don't share percentage ownership or total number of shares outstanding It is your right to ask!

PacBio has officially commercially released Onso, their new short read, high accuracy DNA sequencer. How much of a premium will people be willing to pay for Q40 (and some Q50) reads? #DNA #sequencing pacb.com/press_releases…

More bad news for Illumina. It slashed its sales forecast and two executives left the company. endpts.com/illumina-slash…

It’s lively with some really great discussions (but I don’t like the higher level of anonymity that seems to exist on Discord).

I did not have kind things to say about Ravgen in this Endpoints article by Jared Whitlock endpts.com/his-tiny-prena…

Element is continuing to make nice progress. This means they’ve sold ~50 boxes the last Q and probably have made ~~ $30M in revenue in the past 12 months (LOTS of assumptions in that estimate, don’t @ me 🤣) I think this hurts Singular Genomics more than Illumina

This is a great question:

So Ultima Genomics grabs the top sponsorship. Does that mean they’re finally getting close to a full commercial release?

Chatting Apton Acquisition with PacBio CEO Christian Henry omicsomics.blogspot.com/2023/09/chatti…

I had a blast catching up with Keith Keith Robison and Theral Theral Timpson!

I'm on Xitter less and less these days. I'm currently using a mix of Mastodon and Bluesky for genomics/science stuff (and Threads for entertainment stuff). I have one Bluesky invitation code for anyone who is interested in migrating over.

I’m finding it useful as I spend less and less time here on Xitter.

ONT T2T Genome Bundle: Hot New Thing or Flash in Pan? 🧬🖥️ Where I claim to have invented one piece of ONT’s package omicsomics.blogspot.com/2024/06/ontt2t…

After another year of fresh competition in the DNA sequencing space, there’s a clear loser and clear winner. Surprise twist: it’s the same company! sandiegomics.com/2023-sequencin… #genomics #sequencing