We are very excited to share a new paper out of the lab, led by Stanford Chemistry PhD student, Jason Kronenfeld, in nature ! This work introduces Roll-to-roll CLIP, a new technique for large scale, high resolution production of shape-specific particles! nature.com/articles/s4158…

🚨Only 4 months until Drug Carriers GRS! I’ll co-chair w/ Serena Omo-Lamai as we explore Targeting, Trafficking, and Tropism! 🗣️Top-notch speakers/ mentors include Gaurav Sahay Dr. Simone A. Douglas-Green Mike Mitchell 🗓️Aug 3-4 in Portland, ME ✅Apply ASAP (abstract review has begun)!

ADDR 50 days' free access: A New Era of Targeting Cystic Fibrosis with Non-Viral Delivery of Genomic Medicines. By Gaurav Sahay & coworkers Oregon State COP Gaurav Sahay #GeneDelivery #GeneEditing #CysticFibrosis authors.elsevier.com/a/1ixuf,3sXTmT…

Congrats to my grad student Namratha for her first paper from our lab!

1990 KABANOV LAB While reorganizing my office today, I came across a 1990 institution brochure detailing the research conducted in my laboratory at that time. They say a picture is worth a thousand words. Gaurav Sahay LuxenhoferLab Jacob Ramsey Alyssa Holden Devika S Manickam

Pretty awesome! Alexander Kabanov , a true pioneer of the field.

Always great to meet an old friend, who is doing some great things and leading LNP based delivery efforts at Mount Sinai. Thanks for the invitation Yizhou to visit you and present our work ⁦Yizhou Dong⁩.

Microfluidic Aerosolization Platform: A platform developed by Gaurav Sahay and Oregon State University to preserve the structural and physicochemical integrity of lipid #nanoparticles, enabling efficient delivery of #mRNA to the respiratory system. Learn more: go.acs.org/9dr

A great paper from a friend, collaborator and co-founder of a non-viral eye company that we formed together! Just amazed by Mark and his breadth of expertise and pioneering work on IRDs. I keep learning from every meeting I have with him.

Researchers have developed a device that works in cells & animal models to aerosolize inhalable nanoparticles that can be used to carry mRNA to the lungs, which could lead to advances for gene therapy in patients with lung diseases such as cystic fibrosis. bit.ly/3WAd6Ia

Congrats to Yulia Eygeris and Michael Henderson and our team! Preformed Vesicle Approach to LNP Manufacturing Enhances Retinal mRNA Delivery - Eygeris - Small - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.100…

Nanomaterial researchers recognized with 2024 Kavli Prize in Nanoscience Robert S. Langer, Armand Paul Alivisatos, and Chad A. Mirkin will share the $1 million The Kavli Prize in Nanoscience: cen.acs.org/materials/nano… #KavliPrize2024

We introduce the split-Ugi reaction to modify PEI for RNA delivery! This work was/is more than 4 years in the making! Fantastic work by Kseniia and Andrew, and many more. I am grateful to Gaurav Sahay for this collaboration, and to Cystic Fibrosis Foundation for 💰. Faculty of Science, University of Helsinki Oregon State University

The split-Ugi reaction is perfectly suited to make huge libraries of modified poly(ethylene imine)s for gene delivery, but the innovation does not stop here! We introduce also lipopolymer polyplex lipid hybrid nanoparticles, that greatly outperform in vivo jetPEI!

This has been a fun collaboration! More to come with LuxenhoferLab. Great work by Kseniia, Andrew and team. Robert and I have been collaborators for life beginning from our training days at Sashas’s lab Alexander Kabanov. Now in the hands of peer review process..

Very humbled and honored to be inducted National Academy of Inventors. Really appreciate The Leong Lab Suzie Pun & Bob Langer for the nomination! Thanks to all lab members, collaborators & friends! I believe we will bring more and more inventions to the clinic and benefit patients!

Our summer lab retreat at Haag Lake has become an annual tradition. Started with just four members and now grown and includes our extended family of collaborators at the Casey Eye. Hopefully we keep growing! Pacific Northwest has incredible summers!

Thank you Prof. Katie Whitehead and Vadim for your tireless work putting together an incredible GRC Drug Carriers in medicine and biology meeting. Looking forward to chairing the 2026 GRC with Theresa M. Reineke and working with vice chairs Duvall Lab and @SujathaSonti.

Agreed! Great conference led by Prof. Katie Whitehead and Vadim. And now in great hands of Natalie Artzi Theresa M. Reineke and even beyond that with Duvall Lab and Sujatha Sonti. Also a shout to the excellent GRS organizers Maggie Billingsley, PhD and Serena Omo- Lamai