Congrats to my grad student Namratha for her first paper from our lab!

ADDR 50 days' free access: A New Era of Targeting Cystic Fibrosis with Non-Viral Delivery of Genomic Medicines.
By Gaurav Sahay & coworkers Oregon State COP Gaurav Sahay
#GeneDelivery #GeneEditing #CysticFibrosis
authors.elsevier.com/a/1ixuf,3sXTmT…

🚨Only 4 months until Drug Carriers GRS! I’ll co-chair w/ Serena Omo-Lamai as we explore Targeting, Trafficking, and Tropism!

🗣️Top-notch speakers/ mentors include Gaurav Sahay Dr. Simone A. Douglas-Green Mike Mitchell

🗓️Aug 3-4 in Portland, ME

✅Apply ASAP (abstract review has begun)!

We are very excited to share a new paper out of the lab, led by Stanford Chemistry PhD student, Jason Kronenfeld, in nature ! This work introduces Roll-to-roll CLIP, a new technique for large scale, high resolution production of shape-specific particles!

nature.com/articles/s4158…

From Oregon State University: a new type of lipid nanoparticle that could help deliver gene therapy to the eye (mice and non-human primate models).

PNASNews paper: bit.ly/49ZLiQQ

#NEIfunded OHSU Casey Eye Oregon State COP Gaurav Sahay

Excited to share this Special Feature of PNASNews on RNA Delivery Systems, co-edited with James Dahlman ⁦with contributions from ⁦Doudna Lab⁩ ⁦Feng Zhang⁩ ⁦Prof. Katie Whitehead⁩ and more. pnas.org/topic/564

I love this image of photoreceptor lighting up after delivery of mRNA in the NHP eye ⁦Oregon State University⁩ today.oregonstate.edu/news/researche…

What a great paper! Congrats Amit Tuli!

Excited to share latest study from the lab led by a dedicated & amazing graduate student Kshitiz walia that shows how #ORF3a , a well-known virulence factor of #SARS -CoV-2, blocks #lysosome function by modulating #Rab7 GTPase cycle Nature Communications
nature.com/articles/s4146…
A 🧵

Congrats to Dr(s) Yulia Eygeris, Jeonghwan Kim, Mohit Gupta and team for their persistence and collective effort! Also shout out to Prof (s) James Dahlman and Sangeeta Bhatia for including us in special issue on RNA based nano therapeutics.

Introducing a novel chemistry that enables rational design of lipids for mRNA delivery. In the past, the rate limiting step for retinal delivery with LNPs has been toxicity. We identify new lipids and strategies that enable safe photoreceptor delivery in NHPs.

Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues | PNAS pnas.org/doi/10.1073/pn…

Thank you to CRS Indian Chapter and Vandana Patravale for inviting me to this very exciting meeting in Mumbai. It helped me relive past memories of pharmacy school in Pune and listen to some very exciting talks. Congrats for a great meeting!

What a fantastic start of the symposium!! Thank you Prof Twan Lammers for your outstanding talk. It is really a pleasure to have you as our guest of honour for the 22nd CRS IC International Symposium
Controlled Release Society Young Scientist Committee YSC-CRS Vandana Patravale

Next stop Mumbai! Looking forward to the conference and meeting Vandana Patravale CRS Indian Chapter

I really enjoyed visit to BioAsia in Hyderabad and meeting stalwarts from Indian Pharma Industry and connecting to a booming start-up. Also, “ Genome Valley” consisting of small and large biotech is outstanding!

Gaurav Sahay Jhunjhunwala Lab IISc Bangalore Tanay Bhatt @CCAMP_Bangalore Thank you for your visiting us Gaurav Sahay ! It was a great talk and phenomenal science of drug delivery 🚚
Looking forward to many more interactions. @CCAMP_Bangalore #drugdelivery #mRNA

Thanks to my dear friend Jhunjhunwala Lab for organizing my visit to IISc Bangalore. A phenomenal institute! and Tanay Bhatt for invitation to speak @CCAMP_Bangalore where a lot of innovative companies are getting incubated! Also, found Bangalore to be a lovely city.

A video demonstrating how the device works. More details in the manuscript!