What a beautiful cover art Neuron! :)

Photohormones for the hormone receptor PPARg: Computer-aided exploration of three azologable scaffolds yields a cis-active photoswitchable agonist NYU Chemistry Dirk H. Trauner Sabine Willems @Konstan44550558 Philipp Leippe @BroichhagenJ @FelixH91828753 JMedChem pubs.acs.org/doi/pdf/10.102…

Check out our latest paper on Photohormones thanks to a collaboration with the Merk group in Frankfurt.

Exited to share our latest research article on Nurr1. A systematic study of the chloroquinolineamine scaffold revealed fragment-like Nurr1 agonists and provides insights in Nurr1 regulation. Goethe-Universität ACS Publications Bio & Med Chem Content #nuclearreceptors pubs.acs.org/doi/10.1021/ac…

Online now! Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions dlvr.it/RzZ95l #chembiol

Check out our recent paper Cell Chemical Biology on Vitamin E metabolites as endogenous PPARγ ligands! #nuclearreceptors authors.elsevier.com/c/1d3XZ8jWWJlv…

2 new papers accepted ACS Publications Bio & Med Chem Content within 2 days 😁! Sheers 🥂🥳

Very exited to share our latest highlights in nuclear receptors‘ photopharmacology ACS Publications Bio & Med Chem Content! A PPARα selective photoswitch in living cells🤩 Thanks to this great collaboration with Johannes Morstein Dirk H. Trauner pubs.acs.org/doi/10.1021/ac…

Really pleased to see our Perspective on #nuclearreceptors in neurodegeneration published in J Med Chem ACS Publications Bio & Med Chem Content! #Alzheimers #Parkinson #MultipleSclerosis pubs.acs.org/doi/10.1021/ac…

Online now! Check out our latest findings on #nuclearreceptor Nurr1 now available bioRxiv! Consider in terms of #Alzheimers, #MultipleSclerosis & #Parkinsons Nurr1 modulation mediates neuroprotective effects of statins biorxiv.org/content/10.110…

Could the neuroprotective effects of statins observed in preclinical models of #Parkinsons be modulated by Nurr1? A new bioRxiv manuscript presents evidence suggesting 'yes' biorxiv.org/content/10.110…

Check out our new inverse agonist tool compounds for the neuroprotective #nuclearreceptor Nurr1 ACS Publications Bio & Med Chem Content!🥳 Thanks to my colleagues for this great team effort Goethe-Universität & Fraunhofer-Gesellschaft! pubs.acs.org/doi/abs/10.102…

Check out the article by Sabine Willems from Dr. Daniel Merk's lab at Goethe-Universität reporting on #PPARγ #activation by #vitamin E #metabolites dlvr.it/SBGVfW

This all medicines required to keep ONE covid patient safe for ONE day one critical care…. Or just ONE vaccine? #getthejab

Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue Libraries (Merk) Sabine Willems #OpenAccess onlinelibrary.wiley.com/doi/10.1002/cm…

Very proud to see my first #cover picture! ☺️ thanks to ChemMedChem for this honor!

Finally!! 🥳 Our study on the neuroprotective effects of Statins mediated via #nuclearreceptor Nurr1 is now published by Advanced Science - @AdvSciNews! Thanks for this great collaboration Goethe-Universität and Universität München! 😊 onlinelibrary.wiley.com/doi/10.1002/ad…

📰 EFMC Literature Spotlight of May: “Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue Libraries” (by Daniel Merk in ChemMedChem) 🔗 …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm… ChemMedChem Chemistry Europe ChemistryViews

Now published ACS Publications Bio & Med Chem Content! A perspective on the topic I mainly dealt with during my PhD: Great potential of orphan nuclearreceptor Nurr1 as an emerging target in Neurodegeneration. And my first * , too :) #AcademicTwitter #postdoc pubs.acs.org/doi/10.1021/ac…

Delighted to share our latest collaborative development on photopharmacology and LXR activation from the Dirk H. Trauner and Prof. Daniel Merk's lab. Thanks to the team Sabine Willems Chris Arp and Johannes Morstein