The NKI is looking for outstanding candidates who want to become the new generation of ambitious #PhD students in a lively international research community. Check the website to learn about our #PhDprogram in #MolecularLifeSciences & #CancerBiology ➡️ bit.ly/3Ay8XJL

I am proud to share my PhD paper today online on Nucleic Acids Res. In this work, from Christel Guillouf's and Valentina Boeva labs, with a multiomics approach we dissected the repressive role of SPI1/PU.1 in cooperation with HDAC1 and PRC2 in murine eryhtroleukemia. academic.oup.com/nar/advance-ar…

Many thanks to @Saskia_van_Mil and Eric Kalkhoven and the other organizers of the Nuclear Receptor Research Network meeting that yesterday awarded me with the best poster prize for my research in the @zwartlab. #NRRN #Utrecht #Netherlands #NuclearReceptor #research

snHiC: a complete and simplified snakemake pipeline for grouped Hi-C data analysis by Sebastian Gregoricchio, Ph.D. & Wilbert Zwart in Bioinformatics Advances doi.org/10.1093/bioadv… @zwartlab

🎓We are looking for outstanding candidates who want to become the new generation of ambitious #PhDstudents in a lively international research community. Check our website to learn about our #PhDprogram in #ChromosomeBiology & #GeneRegulation ➡️bit.ly/44iOcOc

Loss of the FANCA pathway, known to control genetic instability, fosters the expansion of leukaemic cells carrying oncogenic mutations nature.com/articles/s4138… Gustave Roussy #Leukaemia #OpenAccess

Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output biorxiv.org/cgi/content/sh… #bioRxiv

... and we used our platform of 19 chromatin-integrated pathway reporters to probe context-dependent effects of epigenetic drugs on Cas9 editing: academic.oup.com/nar/advance-ar…

The first preprint of our PERICODE consortium: MPRA-trained deep learning provides insight into the regulatory logic of promoters and transcription factors. biorxiv.org/cgi/content/sh…

On Thursday I had the opportunity to present my work on endometrial and breast cancer at the #EMBOnuclearReceptors meeting. It was an honor to be able to contribute to the vibrant scientific environment of this conference. @zwartlab The Netherlands Cancer Institute Oncode Institute

🚨Our latest paper out on Genome Biology! We observed a high epigenetic reprogramming in endometrial tumor development, with highly interesting genome/epigenome interplay in endometrial tumorigenesis and disease progression. Many thanks to all coauthors!! genomebiology.biomedcentral.com/articles/10.11…

Favorite study! Germline-somatic tandems dictate cancer subtypes, provide clinical insights, and fuel molecularly informed studies. Kudos: Blerta Stringa, @Paola_Gasperini, Alessandro Alaimo, and Lunardi Lab @ CIBIO (co-last a!) Nima Sharifi doi.org/10.1158/2159-8… Università di Trento