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MotE-like proteins, including FlgY in Campylobacterota and FlbB in Spirochaetota, form characteristic ring structures across bacterial phyla. journals.plos.org/plospathogens/… biorxiv.org/content/10.110… pnas.org/doi/10.1073/pn…

Stunning work from Kai Zhang lab!

Happy to share an update to FollowRelionGracefully! Real-time previews & stats plotting for most #cryoEM #Relion jobs (incl. #teamtomo). Faster, more modular code, uniform UI, & selection. Feedback welcome! github.com/dzyla/Follow_R…

Our new paper about kinesin two head coordination was published rupress.org/jcb/article/22…

Temperature-Sensitive Switch Triggers Sperm Activation, Crucial for Fertility scienmag.com/temperature-se…

You want to start tomography? Solve structures inside cells? Reach Nyquist😳? We have a website for you! tomoguide.github.io You'll find a tutorial on how to reconstruct tomograms, pick particles and do subtomo averaging, using different software! Hope it will be useful !

👏👏 Dutcher elected to National Academy of Sciences source.washu.edu/2025/05/dutche…

Excited to share our new Science Magazine paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals. science.org/doi/10.1126/sc…

I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in Science Magazine ! (link at end of 🧵)

Congrats to MCB's Eva Nogales on her election to the Fellowship of the Royal Society! 👏🎉 The Royal Society The Nogales Lab royalsociety.org/news/2025/05/n…

New story - the structure of the Vault cap at 2.3 Å! Fantastic work by Huan Li (Huan Li). For more details, read the preprint, or check out my thread at the other place! 😊🟦☁️ biorxiv.org/content/10.110…

🎉New preprint!🎉 Extremely excited to share CryoBoltz❄️⚡️, led by superstar Rishwanth Raghu! We develop a multiscale guidance recipe to steer structure prediction models (e.g. AlphaFold3 / Boltz-1) towards experimental cryo-EM density maps, including heterogeneous,

Congratulations to my postdoc Matthew Reynolds Matthew Reynolds on receiving the prestigious Jane Coffin Childs Postdoctoral Fellowship! jccfund.org/fellows/class-… Matt will continue to work on the cytoskeleton within the cellular environment.

New online! Mouse radial spoke 3 is a metabolic and regulatory hub in cilia bit.ly/3TLKkSe

Amazing work from Jun Liu lab! 🤩

CryoDRGN-AI ❄️🐉🤖 is now published in Nature Methods!!! So excited to see this out and a huge congrats to Axel Levy and team! CryoDRGN-AI extends cryoDRGN from requiring input, fixed camera poses, to end-to-end ab initio reconstruction of biomolecules and their conformational

Our Basal Body Story is Now Online! It’s been a long journey. Initially, we plan to understand how the basal body assembles, but along the way, we stumbled upon an unexpected opportunity to explore biogenesis as well.nature.com/articles/s4146…

Our work, co-led by Alfredo Flórez and @NicholasLue, is finally out in NatureStructMolBiol. Shout out to coauthors P.Grob, B. Kaeser, J.Fang, and Susanne Kassube for their contributions, and thanks to the reviewers for their suggestions that led to the final work. nature.com/articles/s4159…

The FASEB Cytoskeleton Conference was a great success! Kudos to chairs Henry Higgs and Sabine Petry for making it happen! events.faseb.org/event/cytoskel…

Excited to share our lab's first preprint — led by our amazing staff scientist, Naseer Iqbal! We show how the dynamic conformation of an SPFH-family membrane assembly enables bacterial recovery during antibiotic stress. Check it out and enjoy! bit.ly/40EDZMl