Rui LU (@ruilulab) 's Twitter Profile
Rui LU

@ruilulab

Assistant Professor at the Division of Hematology & Oncology @UABHeersink @ONealCancerUAB. Exploring epigenetics in cancer and stem cells.

ID: 41297610

linkhttp://www.lu-lab.org calendar_today20-05-2009 04:40:14

591 Tweet

348 Followers

356 Following

NCI Division of Cancer Biology (@ncicancerbio) 's Twitter Profile Photo

Interested in applying for a research grant in basic #cancerbiology? Check out National Cancer Institute Division of Cancer Biology supported #fundingopportunities: cancer.gov/about-nci/orga…

Matt Hurles (@mehurles) 's Twitter Profile Photo

👇👇👇 most important advice to genomics trainees. To understand your data, and its error modes, find a simple informative plot of a slice of your data (read alignment etc) and plot for 100+ random instances. Use your brain’s pattern recognition. Takes minutes, saves months.

Allan-Hermann Pool (@allan_hpool) 's Twitter Profile Photo

First Pool Lab pre-print: bit.ly/3yoewcy. We resolve a major pain with 3’ single-cell RNA-sequencing (10x Genomics etc.) – missing gene expression data from thousands of genes. This stems from suboptimal reference transcriptomes and can easily be recovered. T below: 1/12

Lior Pachter (@lpachter) 's Twitter Profile Photo

Analysis of #scRNAseq requires constant, tedious, interaction with genomics databases. To facilitate querying from Ensembl et al., Laura Luebbert, PhD developed gget: biorxiv.org/content/10.110… (code @ github.com/pachterlab/gget). gget has many uses; a 🧵on the its amazing versatility: 1/

Analysis of #scRNAseq requires constant, tedious, interaction with genomics databases. To facilitate querying from <a href="/ensembl/">Ensembl</a> et al., <a href="/NeuroLuebbert/">Laura Luebbert, PhD</a> developed gget: 
biorxiv.org/content/10.110… (code @ github.com/pachterlab/gget).
gget has many uses; a 🧵on the its amazing versatility: 1/
Rui LU (@ruilulab) 's Twitter Profile Photo

Excited to see this out! This was a fantastic collaboration with Yang Zhou lab, where we did some epigenomics work in direct heart reprogramming. Trained in stem cell and developmental biology, I am always amazed to see how different TFs work together to determine a cell fate.

Gunnar Schotta (@gschotta) 's Twitter Profile Photo

H3K9me3 is not sufficient for silencing endogenous retroviruses if DNA methylation is perturbed. In Dnmt1 ko endoderm cells, IAP elements fully maintain H3K9me3, while trancriptionally active. great collaboration with Heiko Lickert out in Nature Communications rdcu.be/cVRqS

H3K9me3 is not sufficient for silencing endogenous retroviruses if DNA methylation is perturbed. In Dnmt1 ko endoderm cells, IAP elements fully maintain H3K9me3, while trancriptionally active.

great collaboration with <a href="/LickertHeiko/">Heiko Lickert</a>

out in <a href="/NatureComms/">Nature Communications</a>
rdcu.be/cVRqS
Feng Yue (@yuefeng_1) 's Twitter Profile Photo

Excited to share our latest work @nature on 3D genome organization alteration in AML. Great collaboration with Hong Zheng, Leonidas Platanias, MD Aaron Viny Ross Levine Yarui Diao and many others. Led by two outstanding students Jie and Fan. nature.com/articles/s4158…

Jason Sheltzer (@jsheltzer) 's Twitter Profile Photo

Interesting new paper with an important message - normal clone-to-clone variability is an important confounder in CRISPR experiments. nature.com/articles/s4159…

Bingfei Yu (@bingfeiy) 's Twitter Profile Photo

Our work on ENTER is finally out Cell! Like📱that can 📷📞🎧, ENTER is a modular viral platform that unifies multiple applications: ⭐️Decode Ligand-Receptor interaction ⭐️Receptor-specific cargo delivery ⭐️Link receptor specificity with cell state at single cell

Our work on ENTER is finally out <a href="/CellCellPress/">Cell</a>! Like📱that can 📷📞🎧, ENTER is a modular viral platform that unifies multiple applications: 

⭐️Decode Ligand-Receptor interaction
⭐️Receptor-specific cargo delivery
⭐️Link receptor specificity with cell state at single cell
X David Li Lab (@xdavidlilab1) 's Twitter Profile Photo

I would like to share with you our new work on the identification of the first bona fide 'reader' of #histone H3K79 methylation, which has been a mystery since the discovery of this modification in 2002. science.org/doi/10.1126/sc… today online in Science Magazine

Jeremy Baskin (@basktastic) 's Twitter Profile Photo

Do you (want to) use whole-plasmid sequencing (e.g. plasmidsaurus) but are put off by $15/sample? Use SAVEMONEY—Masaaki Uematsu’s algorithm that lets you mix 6 or more plasmids/sample & computationally de-mixes reads! colab.research.google.com/github/Masaaki… biorxiv.org/content/10.110… How it works: 1/n

Do you (want to) use whole-plasmid sequencing (e.g. <a href="/plasmidsaurus/">plasmidsaurus</a>) but are put off by $15/sample? Use SAVEMONEY—<a href="/MasaakiU5/">Masaaki Uematsu</a>’s algorithm that lets you mix 6 or more plasmids/sample &amp; computationally de-mixes reads!
colab.research.google.com/github/Masaaki…
biorxiv.org/content/10.110…
How it works: 1/n
Rui LU (@ruilulab) 's Twitter Profile Photo

Big congrats to my student Sajesan Aryal for being selected by ASH to receive the ASH Graduate Hematology Award (AGHA) [loom.ly/t7i8IC4]! So proud of your work and achievement! UAB Department of Medicine UAB GBS #ASHAwards #proudPI

Big congrats to my student <a href="/SajesanAryal/">Sajesan Aryal</a> for being selected by <a href="/ASH_hematology/">ASH</a> to receive the ASH Graduate Hematology Award (AGHA) [loom.ly/t7i8IC4]! So proud of your work and achievement! <a href="/UABDeptMed/">UAB Department of Medicine</a> <a href="/UAB_GBS/">UAB GBS</a> #ASHAwards #proudPI
UAB Department of Medicine (@uabdeptmed) 's Twitter Profile Photo

🤗 On this #FeelGoodFriday we're thrilled to congratulate GBS student Sajesan Aryal for being named a 2023 ASH Graduate Awardee to pursue his research in the lab of Dr. Rui Lu. We're so proud, Sajesan! Keep up the excellent work! UAB O'Neal Comprehensive Cancer Center Rui LU

🤗 On this #FeelGoodFriday we're thrilled to congratulate GBS student <a href="/SajesanAryal/">Sajesan Aryal</a> for being named a 2023 <a href="/ASH_hematology/">ASH</a> Graduate Awardee to pursue his research in the lab of Dr. Rui Lu. 

We're so proud, Sajesan! Keep up the excellent work!  <a href="/ONealCancerUAB/">UAB O'Neal Comprehensive Cancer Center</a> <a href="/ruilulab/">Rui LU</a>
Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social (@rolanddunbrack) 's Twitter Profile Photo

Demis -- I think AlphaFold3 is really exciting. As Reviewer #3, I got great results from the server. I tried hard to get nature to urge you to release the code but was unsuccessful. I did not get it for re-review so I don't know if you responded. So why no code? Google DeepMind

Anupam Agarwal (@anupamuab) 's Twitter Profile Photo

It is bittersweet to say farewell to Seth Landefeld and wish him well on his next endeavor During his time as chair of UAB Department of Medicine UAB Heersink School of Medicine he has established a path of excellence. His visionary leadership & dedication have left a mark on UAB, inspiring growth & innovation

It is bittersweet to say farewell to Seth Landefeld and wish him well on his next endeavor

During his time as chair of <a href="/UABDeptMed/">UAB Department of Medicine</a> <a href="/UABHeersink/">UAB Heersink School of Medicine</a> he has established a path of excellence. His visionary leadership &amp; dedication have left a mark on UAB, inspiring growth &amp; innovation