Fascinating case report of Brugada syndrome unmasked in a young Indonesian female undergoing lacosamide epilepsy treatment, and found to carry the SCN5A:p.R965C variant. A brief🧵on what is probably the most prevalent rare(ish) Brugada genetic variant: frontiersin.org/articles/10.33…

Excited to share our latest work validating an automated patch clamp assay for SCN5A, now out in Circulation: Genomic and Precision Medicine! ahajournals.org/doi/10.1161/CI… (1/4)

State-of-the-art review on genetics of hypertrophic cardiomyopathy (including some possible future applications) - great to see our latest just published EHJ Editor-in-Chief European Society of Cardiology Journals Carolyn Ho UCL Institute of Cardiovascular Science Barts Health academic.oup.com/eurheartj/arti…

Should patients with cardiac conduction disorders (CCD) be genetically tested? Which 🧬 should be analyzed? What is the contribution of each 🧬? Come with me to see the results of our new study published this week JACC Journals 👇 Long 🧵 (2/16)

Spain were deserved winners. England defined by what was on their bench. Talented players like Palmer, Trent and Watkins who should have been starting. And a mediocre manager who decided not to.

What a performance that was! A perfect routine when it mattered.

One fascinating feature of this famous chart and data set is that, aside from heart disease, Google searches for various causes of death are a pretty good match for actual causes of death. But basically no one ever searches for heart disease, the country’s biggest killer.

Oasis tickets or popcorn queue at #ESCCongress 🤷‍♂️

Excited to share our recent work on cross-biobank and pan-ancestry genetic analyses of rare variants for human disease 🧬 published last week in Nature Genetics Xin Wang Patrick Ellinor Link: nature.com/articles/s4158…

In 2019, our hypertrophic cardiomyopathy gene curation showed 2/3 of "HCM" genes had ltd/no evidence, with 8 sarcomere genes being key We are excited to share the ClinGen HCM re-appraisal > with 29 genes to be included! medrxiv.org/content/10.110…

Celebrating 2024 #NobelPrize winners in Physiology and Medicine by reproposing my personal #JCTR selection of miRNA&CVD review articles from last year👇 #ISCTR Enrique Lara-Pezzi Paul JR Barton Joost Sluijter Anzhela Soloveva Guoping Li Roddy Walsh 🇪🇺 🇺🇦 Laura Iop Nicola Smart Nat Springer