Please read this beautiful piece by my colleague Daniela Robles @daniela-oaks.bsky.social just pub Nature Genetics on coming back home to Mexico 🇲🇽 to do research, the challenges & the opportunities. I echo her sentiment & perspectives starting my new lab LIIGH UNAM LCG UNAM nature.com/articles/s4158…

It is interesting how adult stem cell-derived organoids are overlooked in recent reviews. In a few years, people will think organoids are all derived from ESC & IPSC. The first organoids were made by Mina Bissell more than 30y ago using mammary epithelial cells #justsaying

A pleasure to work with you! The Gri3D array platform is key to upscale this type of assays for applications in drug discovery

#BloodBrainBarrier #Organoid Array Human brain #EndothelialCell (hCMEC/D3) + pericyte + astrocyte Microcavity (φ 600 μm; depth 720 μm) PEG hydrogel > 3000 BBB organoids on a 96-well plate🤠 Dr. Roberto Villaseñor lab Fluids Barriers CNS 2021 Roberto Villaseñor fluidsbarrierscns.biomedcentral.com/articles/10.11…

Researchers applied a novel #bioengineering approach to generate human blood–brain barrier organoids by the self-assembly of astrocytes, pericytes and brain #endothelial cells with unprecedented throughput using micro patterned hydrogels. bit.ly/39zCBzz

Wanna join a fun team working on the cell biology of metabolism Anja Zeigerer in beautiful Munich? We are looking for a postdoc with a 3-year DFG public | @[email protected] funded position. Please RT! Helmholtz Munich | @HelmholtzMunich Helmholtz Diabetes Center (HDC)

The Roche ITB has a brand new website: ritb.roche.com! Super excited to be able to shape the ITB together with an exceptional group of scientists & engineers. A unique institute at the industry-academia interface to unlock the potential of #organoids for drug development

Josephine Lampe, Helge Müller-Fielitz We feel honored to have received the award for the best publication of the Universität Lübeck in 2021 and are grateful for our fantastic team and great collaborators. smleeKRPre, Ümit Özorhan, Roberto Villaseñor, Hauke Busch, Lille Neuroendocrinology, and many more.

Are you interested in cancer organoids/tumoroids and their application in drug discovery and development as well as in personalized medicine? Check out this open postdoctoral position at the Roche Institute for Translational Bioengineering (ITB)! careers.roche.com/global/en/job/…

Both paper and thread are impressive! I wonder if this also plays a role during IT injections 🤔!?

NEW: High Throughput Blood-brain Barrier Organoid Generation and Assessment of Receptor-Mediated Antibody Transcytosis Check out this scalable, consistent, and high-yielding #neuroscience #protocol by Elena Kass Roberto Villaseñor et al. ✔️ bit.ly/3vx8fcR

UPDATE - 🚨 Job opportunity 🚨: good news! if you are a scientist that just** obtained your Diploma/Master's degree, you can also apply for this position. **Within the past 12 months and EU citizen.

Please have a look at this exciting opportunity. Carlos and the team at the ITB are pushing the boumdaries of in vitro human models and their application to drug discovery!!!!

Congratulations on this amazing paper! It is a brilliant approach for receptor id.

It was a super experience to participate at the Brain Barriers meeting in Bari! Great science + great food! Cool findings on barrier regulation, brain delivery and ofc the amazing in vitro models of Martina Colette Bichsel and Lena Jutz.

Bumping this now that hopefully everyone is back from holidays. If you're doing a computational single cell PhD, and you'd like to see what it's like working in industry (I think it's great, personally), please consider applying! And drop me a line if you have any questions :)

New review out from Yosuke Hashimoto in the lab. Everything you ever wanted to know about claudin-5! rdcu.be/c8FC2

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct nature.com/articles/s4146…