🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

I always love commencement time. So much to celebrate and we get to wear our wizard robes! Congratulations to all the graduates! 👏 🤩

Big congrats to grad students Claire Goul Claire Goul and Julian Yano Julian Yano on earning their PhDs from UC Berkeley MCB. Greater adventures await you!

In Nature Genetics we report that base editing of trinucleotide repeats (TNRs) reduces somatic repeat expansions in Huntington’s disease (HD) and Friedreich’s ataxia (FRDA)—in patient-derived cells and in vivo—a collaboration with the Mouro Pinto lab. drive.google.com/file/d/1on7kdy… 1/14

Super happy to share our latest in Nature Cancer co-led by Nick Pannunzio! We review the complex role of the circadian clock in genome integrity, DNA repair, immunity, metabolism, and cancer with a specific focus on early-onset cancer. Check it out! nature.com/articles/s4301…

Thrilled this paper is out! We solved the first cocrystal structure of FSP1 with an inhibitor (FSEN1), providing mechanistic insight & a foundation for medchem. Led by amalia megarioti & Sitao Zhang. A terrific collaboration with Da Jia. Brief Tweetorial! 1/9 pnas.org/doi/10.1073/pn…

Delighted to share our latest study on the complement anaphylatoxin receptors 😎!!! Molecular fingerprints of a convergent mechanism orchestrating diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptors biorxiv.org/content/10.110…

BREAKING: Fareed Zakaria just gave a masterclass on everything that’s wrong with Donald Trump’s second term policies. This is incredible.

Happy to share our latest paper showing that deletion of adipose-derived Isthmin-1 leads to fatty liver and elevated ceramides. Congrats to first author Saranya Reghupaty and all the co-authors! Molecular Metabolism Stanford Pathology Stanford Diabetes Research sciencedirect.com/science/articl…

Excited to announce a new collaboration between the Molecular Therapeutics Initiative (MTI) and Amgen Inc.! This partnership includes funding for cutting-edge research & an internship program for grad students to train in drug discovery & development at Amgen. #MTI #Amgen

Happy to present our latest paper with Ryan Potts & Amgen 🧪🔬🧬 in J. Am. Chem. Soc. by co-first authors Charlotte Zammit & Cory Nadel on the discovery of a direct-acting covalent destabilizing degrader of AR and the undruggable truncation variant of AR, AR-V7, in androgen-independent prostate

Congratulations to Elçin Ünal on her promotion to MCB Professor of Genetics, Genomics, Evolution, and Development! 👏🎉 mcb.berkeley.edu/news-and-event…

Exciting event coming to UC Berkeley MCB Molecular Therapeutics Initiative !

Hard to fathom how anyone can continue to justify the disruption of NIH research by haphazard cuts and destruction when they become aware of stories like this one related to cancer research and clinical trials. cbsnews.com/news/when-is-c…

Final version of our paper showing that a redundant function of several allosteric regulators of glycolytic enzymes HK and PFK is to inhibit the reaction of Harden and Young. Led by Mangyu Choe in collaboration with Tal Einav and Rob Phillips. A 🧵... (1/) cell.com/biophysj/fullt…

Promoted ! 🙌

Exciting event coming to UC Berkeley MCB ,#MolecularTherapeutics, Molecular Therapeutics Initiative !

📣 Paper alert!! Excited to share the 2nd research paper from my time in the BökeLab at Centre for Genomic Regulation (CRG), out today in the The EMBO Journal! We asked: "how do human oocytes regulate proteostatic organelles under physiological conditions?" We collaborated with Dexeus Mujer and employed

Launched today- the Weill Cancer Hub West -supporting transformative cancer research collaborations btw UC San Francisco & Stanford University. Honored to co-lead, with Long Lab, our team who will study the impact of diet on pancreatic cancer initiation, progression and therapy response.

🧬📈 Big win for biotech at UC Berkeley: On July 17, 2025, the UC Regents approved the IGI-Bakar Labs building. The hub will expand lab space for the Innovative Genomics Institute - founded by MTI board member & Nobel laureate Jennifer Doudna - and build out Bakar Labs - the

Our paper on discovering a new paradigm in peroxisome biogenesis and PEX39 (1st human peroxisomal biogenesis protein found in > 20 yr) is out in Nature Cell Biology! Wonderful, equal collab with Tony Rodrigues, Dwendscheck (dwendscheck.bsky.social), Jorge Azevedo, Warscheid lab nature.com/articles/s4155…