I think This makes a pretty good MINEN. Arising from a TVA. 75% of tumor was typical low grade colon adenocarcinoma. This part has high grade NE carcinoma. The LVI goes nicely with the positive LNs that were all the NE component. #GIPath

In thyroid cancer, skeletal muscle invasion represents extrathyroidal spread, but this is only reliable in the lateral lobes and not the isthmus. This is due to Soemmerring's muscle arising from the hyoid bone and inserting on the isthmus. Be careful when assessing tumors here!

High grade serous carcinoma arising in and distending the Fallopian tube #pathology

Nominate our amazing #pathologists colleagues today! Deadline for CAPathologists Meritorious Service Awards is 3/15: capatholo.gy/3rza5b8.

This is simply an amazing example of lymphatic space invasion "caught in the act" in what appears to be intramucosal (muscularis mucosae invasion) carcinoma in a colorectal polypectomy sample. Of course there might be submucosal invasion that simply is not apparent on the slide.

When your antral reactive gastropathy comes with thrombi... That's a GAVE! 👯Gastric Antral Vascular Ectasia👯 🍉Watermelon on endoscopy 🩸Causes bleeding 🫘Assoc. with renal, liver and connective tissue/autoimmune diseases. 💁‍♂️Cd61 great helper! #GiPath #Pathology

Old cases, day 8: esophageal melanocytosis. I’ve only seen this rare finding twice. It may or may not have a relationship with primary esophageal melanoma. bit.ly/3EBKNhP #pathology #gipath #PathTwitter

Gastric biopsies. (Nearly?) impossible case without the clinical history. Any smart cookies with a diagnosis? #GIpath #pathology

Young child, thigh mass #Dermpath #BSTpath #Pathtwitter

A colonic Schwann cell hamartoma, this one forming a nodule. These are generally incidental lesions that arise in adults, described some years ago. #UMiamiPath Am J Surg Pathol. 2009 May;33(5):781-7. PMID: 19065103.

Radiation cystitis with pseudocarcinomatous hyperplasia, closely mimicking urothelial carcinoma. Key diagnostic features: 🔹Fibrin thrombi & vascular congestion (arrows) 🔹Reactive atypia of stromal cells (square box) #PathTwitter #GUPath #MedTwitter #PathResident

Other SOX10+ non melanoma cells in sentinel lymph node: salivary gland tissue inclusion. Although common in paraparotid lymph nodes, they have also been described in unusual sites such as the pulmonary hilum (PMID: 21087984) #pathology #dermpath #dermatology #PathX #MedX

ADH with associated calcifications📘 📸 #pathology #pathtwitter #Breastpath #breastpathology

Colectomy performed for cancer. Colleague's case. Granulomata present away from cancer. On pictures 1 to 3, hard to be sure what they are, but picture 4 shows a viable schistosoma ovum. GI schistosomiasis is usually S. mansoni or japonicum. #GIpath #pathbugs

Mucinous fibroplasia in prostate adenocarcinoma (pathognomic feature of adenocarcinoma) #prostatecancer #GUpath #PathTwitter #MedTwitter #pathX #pathologists #pathology

🔬 Nephrogenic Adenoma ~ Tubules lined by single layer of flattened or hobnailed epithelium ~ #GUpath #Pathology #Urology

‼️Pitfall 🚨 : It's not a cribriform DCIS, it's a moderately differentiated (G2) PDAC showing intratumoural heterogeneity (cribriform glands) #GIPath #PathX #PathResident #PathTwitter #Pathology #surgpath #surgicalpathology

Case of Fibroadenoma with Myxoid Stroma 🔬 Hypocellular myxoid stroma can give fibroadenoma a strikingly distinctive appearance and can be seen both in sporadically or in association with Carney complex. #PathX #PathTwitter #breastpath

Not always easy to recognise #FlatEpithelialAtypia, but hope this composite image may help. On ⬅️ columnar cell change (elongated bland nuclei). On ➡️ FEA - smooth contour, >1 layer, low grade round nuclei (like LGDCIS), not perpendicular to basement membrane. #pathology

🔬 Serous Cystadenoma of the Pancreas: What You Need to Know Serous Cystadenoma of the Pancreas, also known as Microcystic Serous Adenoma, is a rare benign cystic neoplasm that shows a female predominance (3:1), typically diagnosed around the age of 58. It accounts for about