Eortc time at ELCC24 ESMO - Eur. Oncology Mariana Brandao Mario Occhipinti Francesco Cortiula Lodovica Zullo Arianna Marinello, MD Rita Leporati Alessio Cortellini Giovanni Pastorino

What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24, out in Cancer Discovery today rb.gy/q484j9 Tweetorial👇

FLAURA2 exploratory analysis discussion by Marina Garassino at #AACR24: 🔺dynamic ctDNA analysis not useful for clinical decisions 🔹baseline detection of EGFRm is prognostic and may select for a higher degree of clinical benefit from Osi+CT AACR

Congratulations to all of these IASLC Academy participants - early-career physicians interested in academic careers in thoracic oncology, partnered with expert mentors through the year. Looking forward to seeing all that you do!

LIFETIME osimertinib after a treatment with curative intent? In pts with EGFRmut stage III NSCLC, chemo-radiotherapy can CURE pts. Were pts in LAURA properly staged by petscan/brain RMI? Why not using MRD to select patient? Strong concerns when OS is not positive. #ASCO24

Our IASLC Academy is meeting today again!!, very happy to help young oncologists at the begining of their career! Rami Manochakian MD, FASCO Cancer Education #LCSM NO. #LungCancer Fawzi Abu Rous, MD @esinghimd Kaushal Parikh Aakash Desai, MD, MPH, FASCO SOFIA VIDAURRE MENDES Ramila David D. W. Lee, MBBS, FRCR. Rita Leporati @DrSteveMartin

Why do some patients benefit less than others from precision cancer medicine? We are excited to share our paper "Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling” out in Nature Communications. nature.com/articles/s4146… 🧵

#MCCRWorkshop The class of 2024 EORTC - @MyESMO - AACR Workshop

Don’t miss the V edition of the #CocktailWithScience #LungCancer meeting in Milan🫁 👉🏻 lungcancer-milan.com Hosted by Giuseppe Lo Russo with a world-class faculty

🚨🔥The future of #ThoracicOncology is in GREAT hands! The final meeting of the 2024 IASLC #Academy with this OUTSTANDING group of #EarlyCareer #Physicians & #Researchers at #WCLC24. Honored to serve as academy co-chair with my amazing friend Christian Rolfo & GREAT faculty.

Faculty and meentees of our IASLC academy that is meeting today at #WCLC24 with Christian Rolfo Rami Manochakian MD, FASCO Cancer Education @DrSteveMartin Eric K. Singhi, MD Triparna Sen (Sen-Lab) Marina Garassino LudaBazhenovaMD Jyoti D Patel Aakash Desai, MD, MPH, FASCO and many others! #lungcancer #lcsm SOFIA VIDAURRE MENDES

Session on targeted therapy chaired by Drs. Rita Leporati giuseppe viscardi Claudia Proto with Luis Paz-Ares discussing #EGFR: FLAURA2 vs MARIPOSA - longer PFS but cost of toxicity & infusions. Many prognostic factors, need predictive ones. Ivonescimab - is this the future of IO for EGFR?

Today we launched the "ISLB Global Survey: Oncologist Attitudes and Practices on Liquid Biopsy" to collect worldwide data on the use of liquid biopsy in clinical practice! Help us sharing the survey with all the oncologists you know :) docs.google.com/forms/d/e/1FAI…

Excited to share our study on ALK-rearranged NSCLC! We report 3 cases of LCNEC transformation post-ALK-TKI, marking the first reported rate of histologic transformation (4%). Oncologists, be aware of this resistance mechanism! Istituto Tumori Clinical Lung Cancer clinical-lung-cancer.com/article/S1525-…

Quitting smoking within 6 months of a cancer diagnosis improves survival outcomes, with the greatest benefits observed in those who enter cessation programs promptly. ja.ma/4iTDsxr

New review investigates the role of sex differences in NSCLC patients with driver fusions treated with TKIs. Findings show no significant survival differences by sex, but highlight a knowledge gap in sex-specific responses and toxicity data. Read more: journals.sagepub.com/doi/epdf/10.11…

What happens when Young Lung Cancer minds from EORTC meet in Paris? Brains, baguettes & bevs at brasserie Circus! 🧠 🥖 🍷 🍻 Science, collaboration and connections with friends beyond the sessions. #EORTClung #ELCC25 #Younginvestigators #LungCancer #EORTC