My amazing supervisor, mentor and friend, Viktor @VIKorolchuk delivered a talk illustrating how selective autophagy combats ageing and age-related disorders today. I'm really grateful I could travel 4-years journey with him in Newcastle and achieve these progress together!

Happy to share our new paper published in Cell Death & Disease! We showed either FDA-approved autophagy activating drugs or orally bioavailable NAD precursors can promote cell survival including neurons in Niemann-Pick Type C disease models. rdcu.be/dJBSz

Pubs in the UK 🇬🇧

I am excited to share updated information. FINALLY, our paper has been published in eLife! What happens in autophagosomal maturation? We revealed that autophagosomal membranes become negatively charged by PI4P enrichment during maturation. elifesciences.org/articles/92189

I am honoured to coauthor one of my favourite papers of all times when it comes to #mitochondria #ageing and #senescence! cell.com/developmental-… So things are not always as we dogmatically assume. Mitochondrial and "-phagy" dysfunctions are reported to occur with ageing...

Super happy to see the final version of our paper on the role of NAP1/SINTBAD in PINK1/Parkin mitophagy! NatureStructMolBiol Read the full paper here: rdcu.be/dLQgH

Given their popularity, I decided to make a video about mitochondrial membrane potential measurements. I hope it is useful! 𝐖𝐡𝐞𝐧 𝐚𝐧𝐝 𝐇𝐨𝐰 𝐭𝐨 𝐌𝐞𝐚𝐬𝐮𝐫𝐞 𝐌𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐈𝐧𝐧𝐞𝐫 𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞 𝐏𝐨𝐭𝐞𝐧𝐭𝐢𝐚𝐥𝐬 youtu.be/pNqxue0hvPY

Fibroblasts are everywhere in our tissue as structural cells, yet we are only beginning to understand them. Today in nature, we report that lung-specialized alveolar fibroblasts orchestrate lung homeostasis, inflammation, and fibrosis. 🧵👇(1/n) nature.com/articles/s4158…

新曲"エソラゴト" 晩夏公開予定 夏らしい爽やかで神秘的な映像に仕上がりそうな予感です。

【新曲リリース日決定】 約4年ぶりとなる新曲「エソラゴト」 2024/8/31(土) 19時 MV・サブスク解禁！ 『不意に、祝砲が悲劇を告げる。』

━━━━━新曲MV・サブスク解禁━━━━━ 　　　　エソラゴト / Astral Rain 　『不意に、祝砲が悲劇を告げる。━━━━━━━━━━━━━━━━━━━━ □Full MV : youtu.be/Hmwy0oxVhqU □サブスク : linkco.re/UY2AZnxF?lang=…

イギリス生活最後の年に録った新曲「エソラゴト」をとうとうリリースすることができました。 Youtube・各種サブスクからどうぞ 過去曲と印象違うとか、感想あったらぜひ教えてください！

🇬🇧Plz repost!🇯🇵 Our new song is out! For the end of summer. Enjoy via Youtube (youtu.be/Hmwy0oxVhqU?si…) and Apple Music/Spotify/Amazon etc.

Astral Rain - エソラゴト MV監督しました。主演はユキノさん @yukinokkey 様々な夏を回想する今、是非御覧ください。

AMED-PRIME 「老化」領域に採択されました。マイトファジーが細胞の加齢変容を制御するメカニズムに迫ります。帰国して最初の年の、アクセルを踏みたいこの時期に採択され、ありがたい限りです！がんばります。

I'm pleased to announce I'm awarded an AMED-PRIME grant, which is one of the biggest grant for ECR in Japan, for my research project interrogating mitophagy and ageing!

わあ懐かしい music.apple.com/jp/album/your-…

New paper from my laboratory in EMBO Reports doi.org/10.1038/s44319…. Our study challenges what we know about #mitochondria & #aging.

Proud to have contributed to this work: the importance of mitochondrial CI during developmental vs ageing processes. Huge congratulations to Alberto, Rhoda and the team!