A clinical trial is sparking hope for paralyzed patients—literally. Learn how researchers used #spatial and #singlecell technology to understand how electrical stimulation can help people with spinal cord injuries walk again. 10xgen.com/3z1d4w3

What's driving the 'world's fastest-growing' brain disease'? ms.spr.ly/60105NxnY #medtwitter #parkinsonsdisease #NeuroTwitter

A new study shows an association between longer telomere length and healthier brain structures and lower risk for #dementia in older adults. #NeuroTwitter ms.spr.ly/60165CSqQ

Mapping cellular responses to DNA double-strand breaks using CRISPR te... sciencedirect.com/science/articl…

What do High-Intensity Training and #INOCA? have in common? Discover it on #EHJOpen: academic.oup.com/ehjopen/advanc… #OpenUpYourScience EHJOpen Editor-in-Chief Salvatore De Rosa Magnus Bäck Maciej Banach

Middle-aged and older adults with #insomnia disorder may face increased odds of developing subjective memory decline compared with their peers who have only a few or no insomnia symptoms. ms.spr.ly/60145C2AA

Just received Dr. Peter Attia’s new book, OUTLIVE, and I’m thrilled! Over the years, I’ve come to greatly appreciate Peter’s careful, methodical approach to human health. It’s a privilege that we can tap into his unique expertise in this new way. Thank you, @PeterattiaMD!

Dr. Rhonda Patrick Peter Attia When are you going to write that book ✍️ Rhonda? I’d love to place it right by Peter’s on my bookshelf! 📚 🧐Inquiring minds 🧠want to know! 😉 -👨🏻‍⚕️

Great work birgit schilling & Ellerby labs! They defined proteome of human HD medium spiny neurons from isogenic HD iPSCs; top signaling pathways identified incl. extracellular matrix, double-strand break repair & lipid metabolism sciencedirect.com/science/articl… #proteomics #neuroscience

The pathophysiological roles of cGAS-STING inflammatory pathway 美国芝加哥西北大学的Hiroshi Maekawa、日本东海大学的Koichiro Wasano综述了cGAS-STING炎症通路与衰老、自身炎症性疾病、癌症和代谢疾病的关系，这一通路有望成为许多慢性疾病的治疗靶点 journals.physiology.org/doi/abs/10.115…

Congratulations ⁦Zach Gerhart-Hines⁩ ⁦Astrid Linde Basse⁩ ⁦Jonas Thue Treebak⁩ and team ⁦NNF Center for Basic Metabolic Research (CBMR)⁩ thx for agreat collaboration! NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner | PNASNews⁩ pnas.org/doi/10.1073/pn…

#Centenarians have great adaptive immune systems. Study in eBioMedicine – The Lancet Discovery Science finds they harbor distinct immune cell type composition and activity, with highly functional immune systems that have adapted to a history of sickness. Can the rest of us mimic that? eurekalert.org/news-releases/…

Dan Patrick Julia B. Sam Parr David Sinclair Yong Loo Lin School of Medicine Andrea Maier iTR (Induced Tissue Regeneration) Morgan Levine Liz Rose Ocampo Lab AlwaysOmega3s FARIOmega3 Dr. Rhonda Patrick TheHumanAgingProject Université de Sherbrooke UK Biobank Nightingale Health Nature Communications #Atherosclerosis is a systemic pro-inflammatory/pro-oxidative disease, accounting for a third of deaths globally. New systematic review suggests increasing #Omega3/upper limits of daily intake to improve clinical outcomes/reduce risk of cardiac mortality. academic.oup.com/nutritionrevie…

Malpetti et al. report that inflammation in frontal regions is associated with faster cognitive decline in people with a clinical diagnosis of frontotemporal dementia, providing complementary information to measures of grey-matter volume. bit.ly/3ZB1LFw

Our new exciting study on >2,000 individuals uncovers unexpectedly large genetic effects on the human plasma proteome #pQTL in children and adults, among other findings. Check it at shorturl.at/eDOU7 Max Planck Institute of Biochemistry (MPIB) CPRatUCPH Lili Niu Simon Rasmussen Torben Hansen

Genetic conflict with the fetus determines when women give birth Nineteen years of collaborative work. nature.com/articles/s4158…

Weight isn’t determining factor driving joint damage in those who are obese. Research in Uni of Birmingham found #obesity turns specific cells in tissue linking joints into pro-inflammatory ‘bad apples’ that affect entire joint. #cellularsenescence anyone? eurekalert.org/news-releases/…

Organ-specific #aging clocks for multiple #brain and body systems show that the #biologicalage of one organ system selectively influences the aging of multiple other systems via specific aging pathways Ye Ella Tian Andrew Zalesky University of Melbourne UniMelb MDHS nature.com/articles/s4159…

Dan Patrick Julia B. Sam Parr David Sinclair Yong Loo Lin School of Medicine Andrea Maier iTR (Induced Tissue Regeneration) Morgan Levine Liz Rose Ocampo Lab AlwaysOmega3s FARIOmega3 Dr. Rhonda Patrick TheHumanAgingProject Université de Sherbrooke UK Biobank Nightingale Health Nature Communications Uri Alon IdoAmitLab Dr. Axel Montagne, PhD The relationship of #Omega3 fatty acids with #Dementia and cognitive decline: (ADNI3 + prospective cohorts): "Our findings support the hypothesis that the efficacy of omega-3 fatty acid supplementation is dose-dependent. We found that omega-3 fatty acid supplementation was

Dan Patrick Julia B. Sam Parr David Sinclair Yong Loo Lin School of Medicine Andrea Maier iTR (Induced Tissue Regeneration) Morgan Levine Liz Rose Ocampo Lab AlwaysOmega3s FARIOmega3 Dr. Rhonda Patrick TheHumanAgingProject Université de Sherbrooke UK Biobank Nightingale Health Nature Communications Uri Alon IdoAmitLab Dr. Axel Montagne, PhD ADNI3 A new pre-clinical #BrainAging study indicates DHA have more potent anti-inflammatory effects than EPA. #Aging elevated proinflammatory factors TNFα, IL-1β, IL-6 & increased TLR4 & NLRP3. #DHA attenuated most cytokine changes, but EPA only suppressed IL-6. sciencedirect.com/science/articl…