Huge congrats to UMCDB PhD student Renee Conway Hein and team (Joshua Wu @tristanfrum Alyssa J Miller, PhD and collaborators)! R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development, in Developmental Cell cell.com/developmental-… #organoids

Deciphering the consequence of deep intronic variants: a progeroid syndrome caused by a TAPT1 mutation is revealed by combined RNA/SI-NET sequencing medrxiv.org/cgi/content/sh… #medRxiv

Early Embryogenesis and Epiegenetics (EEE) conference Weizmann Institute February 2023- Registration and abstract submission are now open. Will be great fun and many short talks to be selected from submitted abstracts. weizmann.ac.il/conferences/em…

Omics profiling identifies the regulatory functions of the MAPK/ERK pathway in nephron progenitor metabolism An #OpenAccess Research Article from Hyuk Nam Kwon, Kristen Kurtzeborn, Satu Kuure @shkuure and colleagues journals.biologists.com/dev/article/14…

My thesis work is out now in Nature Communications! The #IntegratorComplex is destabilized by rare mutations in INTS13. This change in Integrator function leads to upregulation of a set of ciliary genes, causing a #ciliopathy in 4 individuals nature.com/articles/s4146…

New work from Eric J Wagner and Reversade Lab just out in Nature Communications 👇 Mutations in INTS13 cause a ciliopathy and disrupt Integrator module interactions; the findings underscore the importance of Integrator to human development urmc.info/y2 #URochesterResearch

"In the present manuscript, Wong et al describe for the first time the human phenotype resulting from the bi-allelic germline T543M mutation in the RAF1 proto-oncogene. " Rev #1

Congratulations Franklin Zhong!! NTU Singapore

A great lab Christmas lunch! 🎄

Handmade time-lapse of zebrafish development. Credit to Andro MR. #ZebrafishZunday

Online! A progeroid syndrome caused by a deep intronic variant in TAPT1 is revealed by RNA/SI-NET sequencing. #progeroid_syndrome By A. Mayer, B. Reversade & colleagues Reversade Lab Mayer Laboratory 🗞️#openaccess: doi.org/10.15252/emmm.…

Excellent conference today at #SingaporeFishMeeting2023! And congratulations to Amirah for her poster prize!

📢New today! 📰CIROZ is dispensable in ancestral vertebrates but essential for left-right patterning in humans 🧑‍🤝‍🧑Reversade Lab & colleagues cell.com/ajhg/abstract/…