Our detailed protocol by Ambrocio Sanchez , a graduate student in the lab, revealing our secret to performing perfect in vitro APOBEC deaminase reactions on DNA substrates at near-nucleotide resolution. authors.elsevier.com/a/1kDyIHRzCU0ra

🙌Way to show up! #UCIrvine research team Selma Masri has made it to Round 4 of #STATMadness! We are getting so close to the semi-finals and the championship round. We have a shorter time frame. Submit your votes by Thursday, March 27 at 1 a.m. PT. Let’s go! bit.ly/43piMYT

Today, we report our new study demonstrating that PACT functions as an inhibitor rather than an activator of PKR, and works together with ADAR1 to suppress aberrant activation of PKR by self-derived double-stranded RNA. nature.com/articles/s4146…

A beautiful News & Views by Leonie Unterholzner Lab highlighting our latest paper in NatureStructMolBiol, where we show that transcription stress triggers an inflammatory response through the release of IL-1α. Free link: rdcu.be/ehkTV nature.com/articles/s4159…