Vertebrate retrotransposons are the future of gene therapy. But how do they insert their genes? 🔥🔥 Thrilled to present part 2 of my postdoctoral work with The Nogales Lab Collins Lab UC Berkeley MCB where we investigate this using #CryoEM and transgene insertion in 🧪 and cells!

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by U.S. FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,

Honored to be featured in nature to discuss how AI is quietly revolutionizing one of medicine’s most essential disciplines: pathology. Full article here: nature.com/articles/d4158… Pathology is the backbone of diagnosis, especially in cancer. But today, it faces immense strain

💥Emotions are central to the human experience 😠😳😃☺️😔😕😮🙂 Our Human Neural Circuitry team just took a step towards understanding how they arise–using brain-wide electrical ⚡recordings in humans and mice Science Magazine Read on for more… 1/n

I am deeply saddened by the news of Prof. Gazi Yaşargil’s passing, and so close to his 100th birthday and the yasargil100 Symposium to honor him. I am presenting in Zürich in a few weeks and was greatly looking forward to meeting Dr. Yaşargil, and giving him this portrait. Truly

🧠 Gazi Yasargil — The Greatest Neurosurgeon of All Time 🔬 Father of Microneurosurgery 🛠️ Inventor of aneurysm clips & microsurgical techniques 🎓 Trained hundreds who now lead globally 📖 Author of the classic Microneurosurgery series 🏆 Named “Neurosurgeon of the Century”

A TRUE SOUTH AFRICAN HERO.

Why do some people who have mutations of familial Alzheimer's do not get the disease? They have protective genomic variants. A first-rate review The Lancet Neurology thelancet.com/journals/laneu…

MIT engineers have figured out how to turn skin cells directly into neurons — skipping the stem cell stage entirely. This could fast-track therapies for spinal cord injuries, ALS, and more. news.mit.edu/2025/mit-engin…

Zero-shot antibody design in a 24-well plate biorxiv.org/content/10.110… #biorxiv_synbio

Our latest work is out today in Science Magazine: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development. This was achieved with human midline #assembloids by combining floor plate and spinal cord #organoids

The future of medicine is almost certainly caring for patients collaboratively with agentic AI. We're at the very beginning of figuring out exactly what this will look like in healthcare. At Glass Health, we're bullish on a IDE-like interface with deep EHR integration.

Thanks WIRED Emily Mullin for sharing Mark’s story and what our team has been working on. 🧠🧠 #BCI wired.com/story/synchron…

#ONSNew The Rochester Model for Spinal CSF Leak Repair Simulation and Scoring bit.ly/46Y5kgq by Jalal et al URochester SMD John H. Shin MD, MBA CNS

CRISPR-GPT for Agentic Automation of Gene Editing Experiments biorxiv.org/content/10.110…

🚨 New in Neuro-Oncology Advances: Epigenetics—not mutations—may drive pituitary tumor growth. Our review highlights how DNA methylation patterns influence PitNET behavior, classification, and treatment potential. #NeuroOncology #PitNET #Epigenetics #Neurosurgery #Pituitary