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A historic milestone for modern medicine! Today, a life-changing CRISPR/Cas gene therapy for two severe genetic blood disorders was approved in the UK. time.com/6336222/crispr…

Another first for CRISPR gene therapy. wired.com/story/the-firs…

I had the pleasure of being interviewed for The Cell Therapy Podcast (Gilead Sciences), which is out now on Spotify and Apple Podcast. Had a great talk with Mike Bogetofte Barnkob about applying CRISPR/Cas in advanced cell therapies. Thanks for having me 🙏

CRISPR/Cas course alert ! linkedin.com/posts/rasmus-o…

REGISTRATION IS OPEN !! 2nd Genome Editing for the treatment of Human Diseases ( COST Action CA21113) annual meeting will be held in Limassol (Cyprus) April 8-10. There is an exciting agenda ahead to elucidate the best path for current research applications to benefit patients.

🚀 GenE-HumDi News! 🚀 Are you a young researcher looking to expand your knowledge and network? Look no further! We're thrilled to announce the launch of our new webinar series organized by young researchers, for young researchers.

Still open seats on this CRISPR/Cas course 👇 Application deadline is May 31st.

Beautiful work from our HorizonEU consortium led by Dimitrios L. Wagner and his world-class Berlin team. 90% CAR knock-in with ssDNA templates 😳 Almost couldn’t believe it until we independently produced a batch of ssDNA donor template and replicated it in our own lab. Preprint link 👇

Combining simultaneous up-and-down gene regulation with machine learning model-guided cell engineering: PreciCE: Precision engineering of cell fates via data-driven multi-gene control of transcriptional networks biorxiv.org/content/10.110…

some heads up, The EMBO Workshop "CRISPR-Cas: from biology to therapeutic applications", to be held from 2–5 November 2025 in Sorrento Italy. Please retweet #CRISPR Stay tuned for the programe and registration here 👇 coming-soon.embo.org/w25-86

We report today in Molecular Therapy the development of a trimodal genetic engineering approach combining transcriptional activation (CRISPRa), interference (CRISPRi), and gene knockout - all in a seamless, one-step process. cell.com/molecular-ther…

Our latest News and Views article is out in Nature Protocols. We highlight a protocol from the lab of Omar Abudayyeh and Jonathan Gootenberg that describes integration of large genetic payloads using prime editing and site-specific integrases a.k.a. PASTE. nature.com/articles/s4159…

𝐍𝐞𝐰 𝐓𝐫𝐢𝐩𝐥𝐞-𝐀𝐜𝐭𝐢𝐨𝐧 𝐂𝐑𝐈𝐒𝐏𝐑 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 𝐄𝐧𝐚𝐛𝐥𝐞𝐬 𝐒𝐢𝐦𝐮𝐥𝐭𝐚𝐧𝐞𝐨𝐮𝐬 𝐆𝐞𝐧𝐞 𝐀𝐜𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧, 𝐑𝐞𝐩𝐫𝐞𝐬𝐬𝐢𝐨𝐧, 𝐚𝐧𝐝 𝐃𝐞𝐥𝐞𝐭𝐢𝐨𝐧 𝐢𝐧 𝐏𝐫𝐢𝐦𝐚𝐫𝐲 𝐇𝐮𝐦𝐚𝐧 𝐓 𝐂𝐞𝐥𝐥𝐬 Scientists at Aarhus University have developed a

Orthogonal CRISPR systems for targeted integration and multiplex base editing enable nonviral engineering of allogeneic CAR T Molecular Therapy Rasmus O. Bak 🇩🇰 cell.com/molecular-ther…

Dr. Rasmus O. Bak and team demonstrate a promising strategy for simultaneous multiplex gene knockout and targeted 340 integration to engineer allogeneic CAR T cells in a single step. 🧬 More here: bit.ly/3UMGjh7