Tidyplots empowers life scientists with easy code-based data visualization onlinelibrary.wiley.com/doi/full/10.10…

My lab is recruiting a new PhD student to contribute to studies on anti-IFN autoantibodies and viral disease. The position is fully-funded. Further details: tinyurl.com/UZHPhD Applications MUST be made via the graduate school, deadline 1st May 2025: lifescience-graduateschool.uzh.ch/en.html

The irrigation-induced drying out of the Aral Sea has caused rock deep in the mantle beneath the former lake to uplift and flow like a viscous liquid, at rates of a few millimetres per year, according to a study published in Nature Geoscience. go.nature.com/4j5Xchk

cOmicsArt—a customizable Omics Analysis and reporting tool academic.oup.com/bioinformatics…

PISA: a versatile interpretation tool for visualizing cis-regulatory rules in genomic data biorxiv.org/content/10.110…

that dinosaur guy 🦖 Literally everywhere, but for example in the part where he says that taxonomic rank objections are invalid because rank is arbitrary and in the same breath proposes to expand Canis precisely in the way to retroactively make the company’s marketing claims true:

that dinosaur guy 🦖 …or it could be restricted to exclude Cuon and all the others more basal to Canis lupus, but somehow we’re being asked to arbitrarily concede the option that favors the startup engaging on a PR campaign

New! Online now: Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice dlvr.it/TK6nbW

GeOKG: Geometry-aware knowledge graph embedding (KGE) for Gene Ontology and genes academic.oup.com/bioinformatics…

Making a heatmap is an essential skill for a bioinformatician. But you probably do not understand heatmap. 7 reading resources to understand heatmap! 🧵

Just out in Science (2025)—a landmark study by Christina Jackson, MD et al. identifies a previously uncharacterized immune cell population in human glioblastoma (GBM), termed early myeloid-derived suppressor cells (E-MDSCs) (Michael Lim, MD , Chetan Bettegowda , Hongkai Ji , Drew Pardoll ). These

Happy to announce that my PhD thesis deriving the mathematical theory of the free-energy principle has been awarded the Yael Naim Dowker Prize for Best Maths PhD Thesis from Imperial College London!! 🎉 arxiv.org/abs/2410.11735

Maryna Viazovska, a mathematician from Kyiv, was awarded the Fields Medal in 2022—one of the most prestigious honors in mathematics—for solving the problem of sphere packing in eight-dimensional space. Notably, before her breakthrough, the problem had only been solved in three

I am super happy to annonce that after 9 months under review the first paper of my PhD: scPRINT is finally available on Nature Comms! 🎉🧬 nature.com/articles/s4146…

DataMap: a secure, browser-based ShinyLive application for visualizing high-dimensional 'omics and other data matrices with heatmaps, PCA, and t-SNE arxiv.org/abs/2504.08875 🧬🖥️🧪 #Rstats github.com/gexijin/datamap demo gexijin.github.io/datamap/

Thesis proposal defense done! I’m officially an MS in Microbiology candidate 💛 Endless thanks to my adviser, and everyone in our lab @/PHEIRL. Alsssoooo to everyone who believes in me 🌻

This feels like a mini GPT-2 moment for aging. DeepScence is a deep learning model that detects senescent cells across scRNA-seq and spatial transcriptomics without staining. Outperforms all previous methods. Scalable. Tissue-agnostic.

Always a red flag when people cite a 20yr paper for a question we have much better data on today. On the left is the race/ancestry clustering from Tang et al 2005, and on the right is the race/ancestry clustering for modern biobanks collected over the past few years.

Warm feet promote the rapid onset of sleep.

mRNA's Achilles heel? Short half-life 🧬 Ginkgo Bioworks' study used a 180k-UTR MPRA + ML loop to evolve 3′ UTRs that double mRNA half-life and lift protein output 📈100× in mice🐭 Sequence → assay → redesign becomes a flywheel.