Martini 3 - IDP is out! Improved parameters for disordered proteins, great work from Liguo Wang: nature.com/articles/s4146…

Synthetic peptides targeting a mast cell-specific G protein-coupled receptor MRGPRB2 display anti-infective potential dlvr.it/TL1891 #biomaterials #bioengineering

(1/7) Traditional antimicrobial approaches directly kill bacteria to treat infections. What if we could instead mobilize the body’s own defenses to defeat them? cell.com/cell-biomateri…

Happy to share my first paper from César de la Fuente!

To fight antibiotic resistance, César de la Fuente and @penndentalmed created mirror-image peptides that kill bacteria and boost immunity. Read more about the new contenders to topple superbugs.

We have a postdoctoral opening in the Narayanan Lab (narayananlab.com) UF Chemistry Butler Polymer Research Laboratory. Please apply here: explore.jobs.ufl.edu/en-us/job/5359…

The immune system responds like a forest fire unless you control the spark. Ravi.Radhakrishnan of @cbe_penn Penn Bioengineering and Jake Brenner of @pennmedicine decoded how protein spacing flips the immune “on” switch, paving the way for safer nanomedicine. Read more: bit.ly/4eeGVoG

Online now: Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity dlvr.it/TLf6cn

Thrilled to share our paper on how mitochondrial complex IV remodeling can modulate TAM functions and promote anti-tumor immunity! with Kamen Simeonov, MF Michieletto, Jasmine Wright, Rakesh, César de la Fuente, Andy Minn, JHMLab and those not on X! Out now in Immunity 🎉

(1/3) New in Immunity Cell Press: A single protein inside mitochondria, NDUFA4, keeps some immune cells in tumors “asleep.” Cutting its levels wakes them up, so they start attacking the cancer cell.com/immunity/abstr…

🚨 We are hiring ! 📌 Roles: Sequencing Services – Associate – Business Development (Freshers) – Area Sales Manager – (3–4 yrs experience) 📍 Delhi, Mumbai, Bangalore, Hyderabad, Chennai 📩 [email protected] #Hiring #NGS #BiotechJobs

🚨 We’re hiring! 📌 Roles: – Associate – Business Development, Sequencing Services (Freshers) – Area Sales Manager – Sequencing Services (3–4 yrs experience) 📍 Delhi, Mumbai, Bangalore, Hyderabad, Chennai 📩 [email protected] #Hiring #NGS #BiotechJobs

🚨 We’re hiring ! 📌 Roles: Sequencing Services – Associate – Business Development, (Freshers) – Area Sales Manager – (3–4 yrs experience) 📍 Delhi, Mumbai, Bangalore, Hyderabad, Chennai 📩 [email protected] #Hiring #NGS #BiotechJobs

bioRxiv Genomics Excited to share our paper on the changes in 3D chromatin architecture across cell cycle stages in the pathogenic basidiomycete yeast, Cryptococcus neoformans. Ranjith Padinhateeri Kaustuv Sanyal Dimple Notani Shuvadip Dutta Rakesh Netha

(1/5) Venoms are a vast, largely untapped library of bioactive molecules—and our new paper in Nature Communications Nature Portfolio reveals just how powerful they can be. 🐍⚡️nature.com/articles/s4146…

ft. meg clark, Walter Mowel, MF Michieletto, Leonel Joannas, Jasmine Wright, Isabel Erickson, Jorge Henao-Mejia (Penn Path & Lab Medicine), Lexus Johnson, Andy Minn (Institute for Immunology and Immune Health (I3H)), Rakesh, César de la Fuente (Penn Psychiatry) & Kamen Simeonov (@PennVet) Immunity cell.com/immunity/abstr…

Our new work "Liquid–liquid phase separation of lamin drives altered chromatin organization in cardiomyopathic mutations of lamin A" is now out in NAR. Experiments by Subhradip Nath, Shreyasi & Duhita. Led by mithunmittir & Kaushik Sengupta. 🔗shorturl.at/q5qr3

For over a century, the hunt for new antibiotics has focused almost exclusively on bacteria and fungi. Today, that paradigm shifts. By coupling state-of-the-art AI with the vast, largely uncharted diversity of Archaea, we open a new frontier for molecular discovery. Our APEX

Predicting statistics of gene translocation events: role of chromatin compaction and double-strand DNA break biorxiv.org/content/10.110… #biorxiv_biophys

A paper in Nature Microbiology reports that the use of AI to mine proteomes of archaea led to the discovery of archaeasins, antimicrobials that kill drug-resistant bacteria in laboratory and animal models, offering a promising source of future antibiotics. go.nature.com/3JAdi5C