It was already one month ago that Marta outstandingly defended her thesis! Congratulations again Dr Alaiz!! For the past years, Marta has been working on the role of epigenetic regulation in gene-environment interactions. Good luck in this new chapter! We’ll miss you!

The 2024 FENS has officially begun!  Some of our colleagues are in Vienna, sharing their research with other scientists! Yesterday, Dr. Juan Paraíso presented his fascinating work on the concurrent repressive action of KMDs in neurons. We're so proud! 🧠 #FENS2024

🔥 New review article by BarcoLab is now published on Trends in Molecular Medicine 🔝 This work examines the role of epigenetic alterations, resulting from genetic and environmental influences, as a central factor in ASD, delving into its contribution to pathogenesis & treatment strategies.

📣We're excited to share our latest review article on the role of epigenetics in the etiology of ASD!  Check it out here: shorturl.at/qMZ7E Don't miss it! 📸 Trends in Molecular Medicine

Take a look at our latest book chapter on Engrams! Angel Barco and Miguel Fuentes Ramos have collaborated with other renowned researchers to compile the latest advances on engrams. Their chapter focuses on the underlying transcriptional and epigenetic mechanisms. link.springer.com/book/10.1007/9…

Do you want to be part of our XXI #ChristmasMeeting? 🔝 Save the date! 19-20 December 2024 📍Instituto de Neurociencias UMH-CSIC 👉Applications open until September, 30th

Dejamos atrás el veranito y entramos en septiembre con esta maravillosa imagen de Rafalcala #SciencePhoto_IN

‼️ 📣 We have just published our preview of the work from Eric J. Nestler, MD, PhD lab in Neuron studying the role of H3K27me1 in mouse stress resilience to adult social defeat stress and early life stress. Rafalcala Instituto de Neurociencias UMH-CSIC Neuron Check it out here: authors.elsevier.com/a/1jixA3BtfH9A…

Check out our preview in Neuron about the amazing work done by Eric J. Nestler, MD, PhD lab interrogating the epigenetic basis of stress resilience to adult social defeat stress and early life stress! @barcolab Instituto de Neurociencias UMH-CSIC You can access to it in the following link: authors.elsevier.com/a/1jixA3BtfH9A…

#SciencePhoto_IN "Astro-intrusion" Author: Patricia Torres Lab: Dr. Angel Barco BarcoLab "Primary hippocampal mouse neuron culture. This culture exhibited a remarkable enrichment in astrocytes (immunostained for Gfap). Taken with a confocal Leica Microsystems SPEII."

#SciencePhoto_IN "Invasión Astroterrestre" Autora: Patricia Torres Lab: Dr. Angel Barco BarcoLab "Cultivo de neuronas hipocampales primarias de ratón. Este cultivo muestra un notable enriquecimiento en astrocitos (teñidos con anti-Gfap). Tomada con un Leica Microsystems SPEII."

📣WE ARE HIRING📣 We are looking for a laboratory technician to work with us in the Laboratory of Transcriptional and epigenetic mechanisms of neuronal plasticity based at the Instituto de Neurociencias UMH-CSIC. 🔽Check it out! 🔽

Week of learning, reflecting and practice to go into the good path of leadership ✍️✍️ Thanks to Leadership Sculptor GmbH, EMBO Lab Leadership and the Instituto de Neurociencias UMH-CSIC Severo Ochoa Excellence Program to promote this kind of initiatives

We’re thrilled to see our image on the cover of Trends in Molecular Medicine! The image highlights the crucial role of epigenetics in the etiology of ASD. Many thanks to @IsraelMGuerrero for his collaboration on the design!  shorturl.at/beZqP

Alongside our review, colleague Macarena Herrera shares her experience of researching and living at the beautiful Mediterranean coast, home to Instituto de Neurociencias UMH-CSIC and BarcoLab. 🔬☀️🌊 Take a look!  doi.org/10.1016/j.molm…

Check out our latest paper in collaboration with Charo Robles 🧬 We introduce FrozONE, a protocol for nuclear isolation from frozen tissue that enhances efficiency, reproducibility, and scalability for proteomics. 🔗 Read more: acortar.link/Q7Lr54 Don’t miss it! 🚀

Incredibly happy to share the recent study in which I contributed where we characterized cell-specific epigenetic erosion of developmental genes in HD mouse striatum. Congrats to Baptiste Brulé, Karine Merienne and all the team for this amazing work! 🖥️🔻 nature.com/articles/s4146…

Hoy el #INResearchProgram-Programa de Investigación ‘Bases genéticas y epigenéticas de la individualidad y el envejecimiento’ ha ofrecido un seminario dedicado al PAS Instituto de Neurociencias UMH-CSIC con la presentación del Dr. Rafael Alcalá Vida (BarcoLab) 👏👏

#SciencePhoto_IN “Flying Memory” Author: Mirjam Cangonja Lab: BarcoLab "Viral expression selectively labels hippocampal excitatory neurons. AAV-Cre-mCherry delivery into the dentate gyrus of the hippocampus in CamKII-CreERT2-Sun1GFP transgenic mice. With Thunder Leica Microsystems."

🔥A new study led by BarcoLab at Instituto de Neurociencias UMH-CSIC is published on Cell Reports 🔝 Researchers show that the enzymes KDM1A & KDM5C act as epigenetic guardians, silencing inappropriate genes to keep neuronal identity. More info 👇 in.umh-csic.es/en/articulos/c…