It’s done! LIONESS is out Nature Methods! With the pipeline you can not only create a dense 4D nanoscale reconstruction of living brain tissue, it allows to combine information on morphodynamics, molecular identity and neuronal activity. nature.com/articles/s4159… A 🧵…

⚠️Armstrong Lab Publication Alert⚠️ The work of recent PhD graduate, Tancia W. Bradshaw, PhD, along with fellow grad student, Chad Simmons, and USC College of Arts and Sciences undergrad, Rachael Ott, uncovers the involvement the Ras/MAPK signaling axis in #drosophila fat-to-ovary communication

Improved whole-mount immunofluorescence protocol for consistent and robust labeling of adult Drosophila melanogaster adipose tissue biorxiv.org/cgi/content/sh… #biorxiv_cellbio

Need some guidance on immunolabeling adult #Drosophila fat body? Or just like looking at pretty fluorescent images? Check out this preprint describing work conducted by Rachael Ott, a talented former USC College of Arts and Sciences undergrad.

The Armstrong Lab's (Tancia W. Bradshaw, PhD, Chad Simmons, Rachael Ott) 1st cover courtesy of Developmental Biology! Adipocytes from adult #drosophila females w/ cell membranes in magenta (alpha spectrin Ab from DSHB), lipid droplets in yellow (BODIPY), and nuclei in blue (DAPI)

"Neurons don't get infected with HIV". The absence of evidence is not evidence of absence. Welcome to the 3D superresolution microscopy world. #FluorescenceFriday

#DBfeature #Drosophila 🪰 Ras/MAPK signaling mediates adipose tissue control of ovarian germline survival and ovulation in Drosophila melanogaster by Tancia Bradshaw, Alissa Richmond Armstrong et al Tancia W. Bradshaw, PhD Dr. Alissa Richmond Armstrong 🪰🔬🧑🏾‍🔬 sciencedirect.com/science/articl…

🚨With Jonny Nixon-Abell & @Kosloverlab we are excited to organise  “The Endoplasmic Reticulum Structure and Function Across Cell Types” session at #cellbio2024 #ASCBEMBO! If you are interested in ER, its cellular functions, send us your abstracts by Aug 6🔬 ascb.org/cellbio2024/pr…

Submissions for late-breaking abstracts are now open! Share your most recent and exciting research with a global audience. Submit your late-breaking abstract by Thursday, August 1. 🔗 bit.ly/3YaCp4s #NeuroTwitter #SciTwitter #MedTwitter #AcademicTwitter

Our #TechnicalTuesday post highlights an improved whole-mount IF protocol for consistent & robust labelling of adult Drosophila melanogaster adipose tissue from Rachael Ott Rachael Ott, Isaiah Williams & Alissa Armstrong Dr. Alissa Richmond Armstrong 🪰🔬🧑🏾‍🔬. 📖Biology Open: journals.biologists.com/bio/article/13…

If you need some advice handling adult #Drosophila fat tissue, check out our work spearheaded by former USC College of Arts and Sciences undergrad Rachael Ott and published in Biology Open

Check out our immunofluorescence work this #TechnicalTuesday 🤩 My first first-author paper from undergrad with Dr. Alissa Richmond Armstrong 🪰🔬🧑🏾‍🔬 out now in Biology Open

7/ Optical microscopy is uniquely suited to observe dynamics in living systems and, with the advent of lattice light sheet microscopy (LLSM), we can visualize subcellular dynamics noninvasively at high resolution across all four dimensions of space and time.

New Preprint from Prof Giles Hardingham's lab UK Dementia Research Institute Including beautiful synapse data from Kristján Holt showing microglia are not essential for plaque-associated synapse loss in mice but do influence amyloid pathology deposition biorxiv.org/content/10.110…

One step 4x and 12x 3D-ExM: robust super-resolution microscopy in cell biology. Norman RX, Chen YC, Recchia EE, Loi J, Rosemarie Q, Lesko SL, Patel S, Sherer N, Takaku M, Burkard ME, Suzuki A. doi.org/10.1101/2024.0…

just for the pleasure of it, the fine choreography of epithelial cell migration with a PI3K mutation. This is the complex behavior we have to drug to treat cancer ... Movie from Lucien Hinderling . Switch sound on.

📡🧵 Excited to release our preprint: Ultrack: Pushing the Limits of Cell Tracking Across Biological Scales doi.org/10.1101/2024.0… A tour-de-force by Jordão Bragantini, #Ultrack is a versatile, highly accurate, and fast ILP-based cell tracking software for 2D, 3D, and multicolor

Energy transformation machinery inside mitochondria

Long awaited (thanks James Manton for posting the patent application!) and now out in Science Magazine: Using absorption to look deeper by HongLab - they achieved approx. 3 mm depth using the food dye tartrazine: #Microscopy science.org/doi/10.1126/sc…

Check out these nice orange presynapses lining up on the little gray neuroligin dots! 🟠⚪️🟠⚪️