This post hoc analysis of the TRANSFORM trial suggests cardiovascular morbidity & mortality are similar among de novo #kidney tx recipients receiving calcineurin inhibitors in combination with everolimus or mycophenolate. #VisualAbstract #TransplantTwitter bit.ly/3NCcXhh

The ongoing crisis of kidney disease in Singapore youtu.be/EWOjiWk-CMM

More than 1/3 of patients in our #kidney #transplant cohort had unrepresented #HLA alleles on standard SAB assays. More (>50%!) in minority ethnic groups. We discuss the potential impact of this phenomenon and highlight the uncertainty that remains Singapore General Hospital (SGH) doi.org/10.1111/iji.12…

Protocol for our #TTV monitoring study. Recruitment at ~70%. Hope to make our small contribution for the validation of this promising biomarker to reduce the risk of complications in our #transplant patients!💪🇸🇬 Singapore General Hospital (SGH) SingHealth Duke-NUS Medical School BMJ_Open doi.org/10.1136/bmjope…

Three risk factors for invasive fungal infection across all solid organ transplant groups have been identified: 1.Reoperation 2.Post-transplant renal replacement therapy 3.CMV disease Coop paper by @DrKPennington Raymund Razonable MayoPCCM tinyurl.com/46mxmunx

Fantastic work, and thanks Glenn Glenn J. Hanna, M.D. for pushing over the finish line. It was great to be part of this effort! A potential approach to minimize rejection risk in the setting of anti-PD1 immune checkpoint inhibitor in #kidney #transplantation. Journal of Clinical Oncology

Hemodialysis in non-cooperative patients 👉Nephrologists have a moral obligation to initiate & continue dialysis for non-cooperative patients with a comprehensive, intentional approach using a systematically applied decision framework 📖doi.org/10.1093/ndt/gf…

Original Article by Hullekes et al, "Recurrence of membranous nephropathy after kidney transplantation: A multicenter retrospective cohort study" Frank Hullekes, MD Leonardo V. Riella doi.org/10.1016/j.ajt.…

With tremendous joy, I share that our patient who received a gene-edited pig kidney transplant was discharged home today after removal of his dialysis access. We hope that this is a first step that will bring hope to many patients waiting for a kidney transplant #xenotransplant

#OpenAccess paper by Camille Nelson Kotton et al reporting the second international consensus #guidelines on the management of BK polyomavirus in kidney #transplantation. #Kidneytransplantation #MedTwitter #TransplantTwitter tinyurl.com/49zdvzx6

Not all mismatches are created equal! Take a 👀 here 👇🏻Qualitative, rather than quantitative, differences between HLA‐DQ alleles affect HLA‐DQ immunogenicity in organ transplantation - Maguire - 2024 - HLA - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/ta…

kidney-international.org/article/S0085-…

Thanks to TTS for a great conference! Team TRIG enjoyed hearing all the great presentations and sharing what we have been up to in the lab! #Tregs #spatial

Shortly after a patient received CAR T-cell therapy for relapsed CNS lymphoma, an aggressive CAR+ T-cell lymphoma was diagnosed. Subsequent analysis revealed the presence of an abnormal clone in an early apheresis specimen. Read the Brief Report: nej.md/3BuToVM

Thanks for the shout out Nuffield Department of Surgical Sciences 😆 We had a great time in Istanbul sharing our research with others in the transplant community. TRIG celebrates huge success at International Congress of The Transplantation Society nds.ox.ac.uk/news/trig-cele…

Regulatory cell therapies are promising for reducing immunosuppression burden in transplantation. Read this Review of regulatory cell therapy for kidney transplantation & autoimmune kidney diseases. #OpenAccess link.springer.com/article/10.100…

Everything you need to know about the current state of research in Clinical Immune Tolerance! Out now in Transplantation A big team effort!

Incredibly privileged to be part of this work summarising the current state of clinical immune tolerance research. doi.org/10.1097/tp.000… Transplantation Translational Research Immunology Group Singapore General Hospital (SGH) Duke-NUS Medical School