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Easily my favorite reaction, it’s such a beauty.😄

Very well deserved award!

Truly something special to watch!

How To Choose a Good Scientific Problem (1/3) Molecular Cell #PhD #PhDlife #academics #AcademicChatter #AcademicTwitter #Postdocs #Research #Science

Scripps Research’s Yuzhong Liu, was featured on Spectrum News 1 SoCal for her work on sustainable production of QS-21, a key vaccine adjuvant. Using #synbio, Yuzhong discovered a way to brew QS-21 in yeast instead of relying on the endangered soapbark tree. ow.ly/90ie50TN9Mn

It should come as no great surprise that a Democratic Party which has abandoned working class people would find that the working class has abandoned them. While the Democratic leadership defends the status quo, the American people are angry and want change. And they’re right.

🎄🧬 Happy Holidays from the Keasling Lab 🏳️‍🌈🏳️‍⚧️! 2024 was a year full of scientific breakthroughs and collaborations. May biology continue to solve global problems in 2025 🧬🎄

So it’s going to spend 3 years crippled by insecurity, messing up everything it tries, contemplate quitting as it’s friends get rich and start families, before finally pulling it all together in a manic amphetamine fueled two month stretch and making an amazing discovery nobody

Because AI hallucinations are fundamental to how LLMs work, researchers say that eliminating them completely is impossible go.nature.com/4jywf6p

Glad to share a major piece of my postdoc projects in the KL, and huge thanks to my co-authors & collaborators! We hope this work inspires further PKS engineering to expand biomanufacturing capabilities!

Our scientists are using the unique structure of certain enzymes to create new molecules. They work like building blocks that can be rearranged, and this ability could change the way we make everything from medicines to biofuels.

Announcing Evo 2: The largest publicly available, AI model for biology to date, capable of understanding and designing genetic code across all three domains of life. arcinstitute.org/manuscripts/Ev…

The BioEmu-1 model and inference code are now public under MIT license!!! Please go ahead, play with it and let us know if there are issues. github.com/microsoft/bioe…

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb. go.nature.com/4i9BpEx

Protein function often depends on protein dynamics. To design proteins that function like natural ones, how do we predict their dynamics? Hannah Wayment-Steele and I are thrilled to share the first big, experimental datasets on protein dynamics and our new model: Dyna-1! 🧵

Cell-free synthetic biology for natural product biosynthesis and discovery - now published in Chemical Society Reviews pubs.rsc.org/en/content/art…

Enzymological insights from ensembles bit.ly/3XtQngM

Retrobiosynthesis of unnatural lactams via reprogrammed polyketide synthase bit.ly/4lD8L14

Excited to share plug-and-play engineering of PKSs in two back-to-back papers! We demonstrate two conserved sequences in a PKS module as robust cut sites for PKS reprogramming (rdcu.be/eigV2) and show bioalcohol production by engineered PKSs (rdcu.be/eigVB).

I remember getting the advice that it doesn’t really matter what you focus your graduate work on as long as you find it interesting This analysis suggests otherwise - if you care about impact, choose a research area to commit to for the long haul!