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SPACEtomo v1.2 is online! github.com/eisfabian/SPAC… - Improved GUIs for lamella detection, target selection and CLEM registration make it the best target selection workflow for PACEtomo on any kind of lamella sample. - Easier installation and configuration Any feedback welcome!

Excited to share our paper in EMBO J. on the Nipah virus polymerase !!🦠✨🦇 Using cryo-EM & X-ray, we uncover key roles for the L-protein's Connecting-domain in supporting the PRNTase-domain's capping activity #CryoEM #Nipah #Virology #StructuralBiology embopress.org/doi/full/10.10…

Interested in joining our growing interdisciplinary team studying viruses, RNA, and condensates? Looking for a postdoctoral position? Please consider joining us in Cambridge, UK, or drop us a line to discuss these opportunities: jobs.cam.ac.uk/job/49901/

The entire science journal system should be scrapped - every single bit of it - and any institution that continues to participate in it, support it or pay for it is doing a grave disservice to science and society.

The outgoing Chair of the Science and Technology Committee, Baroness Brown, has written on behalf of the Committee to the Home Secretary, Rt Hon Yvette Cooper MP, concerning the UK’s immigration and visa policies for STEM talent. Read it here: committees.parliament.uk/publications/4… THREAD 1/

Pranav N. M. Shah et al.: TomoCPT: a generalizable model for 3D particle detection and localization in cryo-electron tomograms #CryoET #ParticlePicking #SubTomogramAveraging University of Oxford @IEUniversity... #IUCr journals.iucr.org/paper?S2059798…

The February issue is available! tinyurl.com/3t4hk7wa The cover highlights TomoCPT, a transformer-based solution that reformulates particle detection in cryo-ET as a centroid-prediction task using Gaussian labels. tinyurl.com/45w6cwvp

Interesting in learning to process cryo-ET data in the latest version of Warp? I'll be running a workshop on April 22nd in central London, UK details+registration: forms.gle/u4Hk73jhenMvpN… Hope to see you there!

New Research Assistant position in the group. #cancer #vaccine my.corehr.com/pls/uoxrecruit…

TomoCPT is a transformer-based solution that reformulates particle detection in cryo-ET as a centroid-prediction task using Gaussian labels  University of Oxford @IEUniversity Structural Biology IUCr #CryoET #ParticlePicking #SubTomogramAveraging doi.org/10.1107/S20597…

3D manual picking tool along microtubules

This is by far the best QoL improvement you can do to your ChimeraX (bsky: chimerax.ucsf.edu) experience. Honestly, it should be the default standard for the package.

Exciting news! We have two postdoc positions opened in our lab FLORIDA! Study gut hypoxia & virus immunity OR immunity and intracellular trafficking in polarized cells. Come do cool science with a fun team! Check out all details: boulantlab.com/opportunities #PostdocJobs #ScienceTwitter

Come join our community! Looking for highly motivated post docs to join our team!

I met Cédric Villani, the Fields medallist mathematician in Sweden, when he was invited to give a plenary talk, celebrating the 100th anniversary of Institut Mittag-Leffler. After his lecture, we had a short conversation; completely unremarkable to him, profoundly impactful to

I have been on this exact same journey… i 100% resonate with the entire arc, except the 1-arm push up bit 🤣

Building atomic models to cryo-EM maps of huge molecules is intimidating: crowded, uncertain copy numbers, variable resolution ... Fan Liu lab and team show how cross-linking MS can be used to build novel models of unknown complexes, like a giant virus❄️ ❄️biorxiv.org/content/10.110…

Our method paper for HIV-1 nuclear import is out now in EMBO reports! Check it out here: doi.org/10.1038/s44319… the Peijun Zhang Lab Yao Shen STRUBIOxford Nuffield Department of Medicine eBIC Beamline Diamond Light Source EMBO Reports

You should be so lucky to have people throughout your research career that you can openly bounce ideas to and from - especially if they complement your strengths in your areas of weakness - it is a rare and precious gift.

Nature used to be the world’s most prestigious science journal. Now it’s one of many accused of favouring authors because of their identity group rather than the excellence and importance of their science. hxstem.substack.com/p/why-i-no-lon…