Syed A Hussain (@profsyedhussain) 's Twitter Profile
Syed A Hussain

@profsyedhussain

Professor of Medical Oncology Department of Oncology and Metabolism Medical School, Beech Hill Road, Sheffield

ID: 760569166239760384

linkhttp://www.sheffield.ac.uk/oncology-metabolism/staff/hussain calendar_today02-08-2016 20:13:14

597 Tweet

716 Followers

525 Following

Dr. Bishoy M. Faltas (@faltaslab) 's Twitter Profile Photo

🚀Big News! Excited to share our work “The Interplay of Mutagenesis and ecDNA Shapes Urothelial Cancer Evolution” published in nature! nature.com/articles/s4158…

🚀Big News! Excited to share our work “The Interplay of Mutagenesis and ecDNA Shapes Urothelial Cancer Evolution” published in <a href="/Nature/">nature</a>! nature.com/articles/s4158…
Yüksel Ürün (@dryukselurun) 's Twitter Profile Photo

🧬In MIBC, deleterious DDR gene alterations, especially ERCC2, show promise as markers for better response to cisplatin-based chemotherapy. 🧬Patients with these alterations had higher rates of pathologic response, suggesting the potential for personalized NAC strategies in

🧬In MIBC, deleterious DDR gene alterations, especially ERCC2, show promise as markers for better response to cisplatin-based chemotherapy. 
🧬Patients with these alterations had higher rates of pathologic response, suggesting the potential for personalized NAC strategies in
OncoAlert (@oncoalert) 's Twitter Profile Photo

Join us for the GUARD Symposium🇪🇸 featuring interactive workshops where experts collaboratively discuss real-world genitourinary cancer cases. REGISTER👉 events.tacticsmd.net/guard-internat… ⭐️FREE VIRTUAL Admission for LMIC's & LATAM Colleagues⭐️ Here is our Colleague Dr. Felipe Couñago PhD🇪🇸 with

Syed A Hussain (@profsyedhussain) 's Twitter Profile Photo

It was great to attend ASCO2025 in Chicago.Some exciting &practice changing data was presented. Highlight was to connect with so many of my friends. Our ongoing trial NEOWIN was presented as well. ⁦Enrique Grande⁩ ⁦Andrea Necchi⁩ ⁦Yoan Loriot⁩ ⁦ASCO

It was great to attend ASCO2025 in Chicago.Some exciting &amp;practice changing data was presented. Highlight was to connect with so many of my friends. Our ongoing trial NEOWIN was presented as well. ⁦<a href="/drenriquegrande/">Enrique Grande</a>⁩ ⁦<a href="/AndreaNecchi/">Andrea Necchi</a>⁩ ⁦<a href="/YLoriot/">Yoan Loriot</a>⁩ ⁦<a href="/ASCO/">ASCO</a>⁩
OncoAlert (@oncoalert) 's Twitter Profile Photo

Join us for the GUARD Symposium🇪🇸 featuring interactive workshops where experts collaboratively discuss real-world genitourinary cancer cases. REGISTER👉 events.tacticsmd.net/guard-internat… ⭐️FREE VIRTUAL Admission for LMIC's & LATAM Colleagues⭐️ Here is our Colleague Dr. Ainara Azueta🇪🇸

OncoAlert (@oncoalert) 's Twitter Profile Photo

Day One 🚨 #GUARDSymposium2025 AI in diagnostic imaging being presented by Dr. Almudena Fuster AI is revolutionizing genitourinary oncology diagnostics by overcoming the limitations of traditional imaging. Radiomics, a key AI application, extracts valuable quantitative data

Day One 🚨 #GUARDSymposium2025
AI in diagnostic imaging being presented by Dr. Almudena Fuster

 AI is revolutionizing genitourinary oncology diagnostics by overcoming the limitations of traditional imaging. Radiomics, a key AI application, extracts valuable quantitative data
Dra. María Natalia Gandur Quiroga (@nataliagandur) 's Twitter Profile Photo

🌟🔵 Redefining metastatic hormone-sensitive prostate cancer Javier Puente OncoAlert #GUARDSymposium2025 🔹 Timing & burden define prognosis in mHSPC 🔹 Drug selection = disease + patient + regimen factors 🔹 Triplet therapy: 94% support in high-volume, fit patients 🔹 APCCC vote:

🌟🔵 Redefining metastatic hormone-sensitive prostate cancer
<a href="/docjavip/">Javier Puente</a> <a href="/OncoAlert/">OncoAlert</a> #GUARDSymposium2025

🔹 Timing &amp; burden define prognosis in mHSPC
🔹 Drug selection = disease + patient + regimen factors
🔹 Triplet therapy: 94% support in high-volume, fit patients
🔹 APCCC vote:
OncoAlert (@oncoalert) 's Twitter Profile Photo

A GREAT DAY TWO of #GUARDSymposium2025 JOIN US TODAY FOR THIS FINAL DAY REGISTER👉 buff.ly/r4vwa6B STILL NOT TOO LATE TO JOIN US VIRTUALLY!!! ⭐️FREE VIRTUAL Admission for LMIC's & LATAM Colleagues⭐️ Tom Powles Syed A Hussain Matt Galsky Andrea Necchi Félix Guerrero-Ramos

A GREAT DAY TWO of #GUARDSymposium2025 JOIN US TODAY FOR THIS FINAL DAY
REGISTER👉 buff.ly/r4vwa6B

STILL NOT TOO LATE TO JOIN US VIRTUALLY!!! ⭐️FREE VIRTUAL Admission for LMIC's &amp; LATAM Colleagues⭐️

<a href="/tompowles1/">Tom Powles</a>
<a href="/ProfSyedHussain/">Syed A Hussain</a>
<a href="/MattGalsky/">Matt Galsky</a>
<a href="/AndreaNecchi/">Andrea Necchi</a>
<a href="/DrFelixGuerrero/">Félix Guerrero-Ramos</a>
Dra. María Natalia Gandur Quiroga (@nataliagandur) 's Twitter Profile Photo

🌟🔵 Rethinking high-risk NMIBC: from BCG to future paradigms Félix Guerrero-Ramos OncoAlert #GUARDSymposium2025 A powerful session bridging evidence & real-world barriers 🔹 BCG works → still cornerstone therapy (solo or in combo) 🔹 CREST: BCG + systemic chemo ↓ CIS & high-grade

🌟🔵 Rethinking high-risk NMIBC: from BCG to future paradigms
<a href="/DrFelixGuerrero/">Félix Guerrero-Ramos</a> <a href="/OncoAlert/">OncoAlert</a> #GUARDSymposium2025
A powerful session bridging evidence &amp; real-world barriers
🔹 BCG works → still cornerstone therapy (solo or in combo)
🔹 CREST: BCG + systemic chemo ↓ CIS &amp; high-grade
Dra. María Natalia Gandur Quiroga (@nataliagandur) 's Twitter Profile Photo

🌟🔵 Perioperative IO in MIBC: where are we heading? Presentation by Dr. Andrea Necchi #GUARDSymposium2025 OncoAlert Advanced Prostate Cancer Consensus Conference 🌟Critical questions remain: pCR utility, timing, IO-only options 🔹 Neoadjuvant: better compliance, early systemic control & biomarker discovery

🌟🔵 Perioperative IO in MIBC: where are we heading?
Presentation by Dr. <a href="/AndreaNecchi/">Andrea Necchi</a>  #GUARDSymposium2025
<a href="/OncoAlert/">OncoAlert</a> <a href="/APCCC_Lugano/">Advanced Prostate Cancer Consensus Conference</a>
🌟Critical questions remain: pCR utility, timing, IO-only options
🔹 Neoadjuvant: better compliance, early systemic control &amp; biomarker discovery
Dra. María Natalia Gandur Quiroga (@nataliagandur) 's Twitter Profile Photo

🌟🟠 Bladder Sparing in MIBC Presented by Matt Galsky @MountSinaiCancer OncoAlert @GUARDConsortium #GUARDSymposium2025 👀 Patient selection is key. Should all that can be done actually be done? 🔵 TURBT + systemic tx remains limited by historical barriers: lack of biomarkers,

🌟🟠 Bladder Sparing in MIBC
Presented by  <a href="/MattGalsky/">Matt Galsky</a> @MountSinaiCancer
<a href="/OncoAlert/">OncoAlert</a> @GUARDConsortium #GUARDSymposium2025
👀 Patient selection is key.
Should all that can be done actually be done?
🔵 TURBT + systemic tx remains limited by historical barriers: lack of biomarkers,
Yüksel Ürün (@dryukselurun) 's Twitter Profile Photo

Durvalumab approved in the 🇪🇺EU as the first and only perioperative immunotherapy for muscle-invasive bladder cancer. Based on NIAGARA trial: 32% ⬇️recurrence risk, 25%⬇️ risk of death. Proud to be part of this journey as a study site. OncoAlert World Bladder Cancer Patient Coalition Tom Powles

Durvalumab approved in the 🇪🇺EU as the first and only perioperative immunotherapy for muscle-invasive bladder cancer.
Based on NIAGARA trial:
32% ⬇️recurrence risk, 25%⬇️ risk of death.
Proud to be part of this journey as a study site.
<a href="/OncoAlert/">OncoAlert</a> <a href="/WorldBladderCan/">World Bladder Cancer Patient Coalition</a> 
<a href="/tompowles1/">Tom Powles</a>
Yüksel Ürün (@dryukselurun) 's Twitter Profile Photo

U.S. FDA approves durvalumab for perioperative immunotherapy for patients with muscle-invasive bladder cancer In a prespecified analysis, the trial demonstrated a statistically significant improvement in event-free survival and overall survival. American Cancer Society Suresh S. Ramalingam, MD, FASCO

<a href="/US_FDA/">U.S. FDA</a>  approves durvalumab for perioperative immunotherapy for patients with muscle-invasive bladder cancer
In a prespecified analysis, the trial demonstrated a statistically significant improvement in event-free survival and overall survival.
<a href="/AmericanCancer/">American Cancer Society</a> <a href="/RamalingamMD/">Suresh S. Ramalingam, MD, FASCO</a>
Syed A Hussain (@profsyedhussain) 's Twitter Profile Photo

Great to see the international collaborations moving the field forward and answering questions within randomised trials to further improve clinical outcome & QOL gains for our patients globally. Kari Tikkinen Yüksel Ürün jim catto Enrique Grande ASCO The University of Sheffield Daniel Castellano