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Proud to see SAMap used for such beautiful work! It was designed to map scRNAseq datasets across species but ended up able to be used for scATACseq data as well!

I am thrilled to share the published version of our study on how neuropeptide signals regulate feeding in the hypothalamus! We imaged endogenous peptide signals in subcellular compartments during behavior. Below is an updated summary: rdcu.be/dZlI3

Just out in Nature, we reveal a key molecular signature that evolution drew upon to boost photosynthesis—the process responsible for fixing CO2 (and sustaining life as we know it). Together with the brilliant Leonie Luginbuehl, Joe Ecker, and Julian Hibberd nature.com/articles/s4158…

How to survive without water for months without feeling thirsty? A new manuscript by Maddy Junkins in the Gracheva lab: science.org/doi/10.1126/sc…

Several years in the making (and aging), Xueqian Zhuang 's study on aging is out today nature. She finds, surprisingly, that aging suppresses tumorigenesis and stemness in the lung by promoting a functional iron insufficiency in the alveolar epithelium. nature.com/articles/s4158…

In eLife - the journal: Distinct functions of three Wnt proteins control mirror-symmetric organogenesis in the C. elegans gonad doi.org/10.7554/eLife.…

Intermittent fasting triggers interorgan communication to suppress hair follicle regeneration: Cell cell.com/cell/fulltext/…

It is just so sad that the #NeurIPS2024 main conference ended with such a racist remark by a faculty when talking about ethics. How ironic! I also want to commend the Chinese student who spoke up right on spot. She was respectful, decent, and courageous. Her response was

nature.com/articles/s4158… (1/n) Ever wonder how transcription factors locate, "invade," and activate their enhancers during cell fate acquisition? 🧬🚀Check out our latest collaborative work with the Soufi lab, now published in nature!

After reading this, one question plagues me: does metformin play a role in healthspan through modulating cell competition across various tissues? Super easy to test if access to tissue. Congrats to the authors!!! ⁦valentina greco⁩ nature.com/articles/s4155…

Paper alert🐟! Thrilled to share that our latest study “BMP signaling promotes zebrafish heart regeneration via alleviation of replication stress” nature.com/articles/s4146… is now live in Nature Communications. We show how BMP alleviates this stress via a conserved mechanism in mammals🐭

Online Now! Sustained NF-κB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation dlvr.it/TJ4BrB #stemcells

nature.com/articles/s4158…

I love that after all the money poured into genome mining and large scale screens, the first new class of antibiotics in decades came from some guy’s garden... nature.com/articles/d4158…

Check out our new paper in Nature Biotechnology sharing our latest kinase activity reporters! Led by former postdoc Michelle Frei, these reporters are based on HaloTag rather than an FP, for far-red imaging and superresolution! nature.com/articles/s4158…

5/10 How is this achieved? We found that PV interneurons induce the expression of two genes encoding multiple neuropeptides, Scg2 and Vgf, in response to increased activity

Systemic effects in #axolotl regeneration: Check out this great contribution from the Echeverry lab to our special edition ⁦npj Journals⁩ Regenerative Medicine nature.com/articles/s4153…

Not sure how many people realize that battery storage already supplies 30% of California’s electricity demand at peak. Batteries aren’t the future — they’re here now.

Two Princeton professors, a husband-and-wife team, traveled to the Galápagos Islands every summer for ~40 years to watch evolution happen in real-time. They weren't studying fossils. Rather, they were measuring the beaks of Darwin's finches. And it paid off. Their names are