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PPIs linked to higher acute kidney injury risk vs. H2RAs in septic patients at high stress ulcer risk 🚨🩺 #AKI #Sepsis #ICU #PPIs #H2RAs

🆕️⚡️⚡️ Pharmacotherapy SIDP Katie Olney Amit Pai Fixed dose daptomycin*: An opportunity for pharmacokinetic/pharmacodynamic optimization in Staphylococcus aureus infections #IDXposts * 750mg accpjournals.onlinelibrary.wiley.com/doi/full/10.10…

A characterization of the risk of digoxin toxicity in older adults taking digoxin following co-prescription of TMP-SMX compared with co-prescription of amoxicillin. OPEN ACCESS: buff.ly/4bu8ZBg ACCP Cardiology PRN

Study Alert: TMP-SMX increases digoxin toxicity risk nearly 6-fold in older adults compared to amoxicillin—consider alternative antibiotics or dose adjustment! 🚨💊 #Pharmacy #PatientSafety #Geriatrics

Recommendations to assist clinicians in optimizing use of 5 long-acting ARVs that are currently available in a limited number of countries worldwide for the prevention or treatment of HIV-1. OPEN ACCESS: buff.ly/4cYxUhn ACCP @AAHIVMcomm @HIVclinic EACS SIDP

A snapshot of microbiology, pharmacology, and clinical data for currently available BL/BLI treatment options as well as agents in late stage development for CRO harboring various β-lactamases including MBL and OXA-enzymes. buff.ly/4f69zZc ACCP INFD PRN

An overview of the development process and recommendations made for the use of long-acting antiretrovirals for the treatment and prevention of HIV-1. buff.ly/4dru1Sq ACCP @AAHIVMcomm @HIVclinic EACS SIDP ACCP HIV PRN

Compared with traditional antiplatelet or thrombolysis, GP IIb/IIIa antagonists administered w/in 24–96 h of ischemic stroke onset significantly improve functional prognosis of pts with acute ischemic stroke not receiving endovascular therapy. OPEN ACCESS: buff.ly/3W6UJbW

SGLTI effects on obesity, metabolic dysfunction-associated steatotic liver disease, polycystic ovarian syndrome, abnormal lipid metabolism, hyperuricemia, obstructive sleep apnea syndrome, anemia, and syndrome of inappropriate antidiuresis. buff.ly/46lOBl7

This study quantified the probability of toxicity and efficacy end points by prospectively testing a fixed dose regimen of daptomycin (750 mg) in obese and non-obese adults. buff.ly/3WIS4FD #accpinfdprn

Fixed Daptomycin Dosing: Effective but Needs Monitoring Study finds: 1. Consistent drug levels, but monitoring is crucial. ✅🔍 3. Adjusted dosing may improve care, but patient-specific monitoring is key. 🩺📊 #Antibiotics #Daptomycin #Healthcare #Pharmacology #PatientCare

Normal saline is recommended by the American Diabetes Association; however, this study compared lactated Ringer's to normal saline in the acute management of DKA buff.ly/4clyYLQ ACCP CRIT PRN

The prevalence of AKI was higher among patients who received polymyxin B compared to those treated with colistin sulfate. However, there was no significant difference in 30-day all-cause mortality between the two groups. buff.ly/3StlqGP ACCP INFD PRN

An overview of the development process and recommendations made for the use of long-acting antiretrovirals for the treatment and prevention of HIV-1. buff.ly/4dru1Sq ACCP @AAHIVMcomm @HIVclinic EACS SIDP ACCP HIV PRN

This study quantified the probability of toxicity and efficacy end points by prospectively testing a fixed dose regimen of daptomycin (750 mg) in obese and non-obese adults. buff.ly/3WIS4FD ACCP INFD PRN

Normal saline is recommended by the American Diabetes Association; however, this study compared lactated Ringer's to normal saline in the acute management of DKA buff.ly/4clyYLQ ACCP CRIT PRN

Congratulations to ACCP member David S. Burgess and co-authors on the recent publication of their article in Pharmacotherapy! Access the abstract and/or article here: ow.ly/jLJB50T9JyB   #MakingAnImpact #TwitteRx #ACCP Pharmacotherapy

Predictive and observational results in adults, children, and the drug-drug interaction model were in good agreement. Learn more at: buff.ly/4dLUZ84

Incretin hormone agonists represent a significant advancement in the pharmacotherapy of #obesity, a significant global health challenge, affecting over 800 million individuals worldwide. buff.ly/3Xa0wOI