Hey Elon Musk Tesla - love to see the value of our new car drop this morning for no reason! Thanks! Maybe give current owners some incentive to buy another Tesla in the future? If so, I have some ideas. #goodbusiness #tesla

From the platform that makes human genetics & genomics available for researchers for #T2D, out in preprint today, is our new work outlining a resource for #T1D: t1d.hugeamp.org Common Metabolic Diseases Knowledge Portal Common Metabolic Diseases Genome Atlas Kyle Gaulton Stephen Rich biorxiv.org/content/10.110…

Introducing the Type 1 #diabetes Knowledge Portal #T1D t1d.hugeamp.org biorxiv.org/content/10.110…

How will rare genetic variation inform our understanding of common disease? Today in nature, we’re excited to share our answer to this question, with a new method and insights from nearly 400,000 exomes: nature.com/articles/s4158… 🧵 (1/15):

Instead of putting hard thresholds for sample size, I'd recommend advocating for good study designs, statistical power consideration, replication effort and better phenotyping.

Interesting paper arguing for the clinical use of PRS to identify men at risk of prostate cancer despite lower PSA levels in their mid-life (and so typically do not undergo routine PSA screening)

Looking for a postdoc position? This is your chance to get not just one, but TWO amazing mentors. Apply for this position with Miriam Udler and Jason Flannick to work at the cutting edge of diabetes precision medicine! broadinstitute.wd1.myworkdayjobs.com/broad_institut…

Do you want to get more out of human genetics, but don’t know where to start? Our new paper (authors.elsevier.com/sd/article/S15…) describes how the T2DKP (type2diabetesgenetics.org) is designed for people like you. 🧵

The Type 2 #Diabetes Knowledge Portal #Genetics T2DKP: toward the goal of democratizing access to complex disease genetic results Cell Metabolism Jason Flannick cell.com/cell-metabolis…

Congrats to the Common Metabolic Diseases Knowledge Portal team!! Amazing work

New! Online now: The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits dlvr.it/SlMZR0

This resource published today is only possible through the "first-to-commit" in 2015 to open sharing of data by the #T2DGENES #SIGMAT2D #GoT2D consortia - founded on trust & partnership to present these results. Broad Institute NIDDK Foundation for the National Institutes of Health Common Metabolic Diseases Knowledge Portal Common Metabolic Diseases Genome Atlas

The T2D Knowledge portal comes with a set of carefully developed analytic tools, providing a valuable, ongoing resource for the entire scientific community and tremendous benefit for patients long-term. Read more: ow.ly/rJMR50NzV47

NIDDK is proud to partner with Foundation for the National Institutes of Health, Broad Institute, and others to provide the AMP-T2D Knowledge Portal, enabling researchers to access data and tools to explore new approaches in understanding T2D and developing new treatments. -GR cell.com/cell-metabolis…

Our article on the T2DKP is illustrated on the cover of today's issue of Cell Metabolism! Find the details here: t2d.hugeamp.org/news.html?nid=… or go straight to the article here: cell.com/cell-metabolis… Broad Institute Foundation for the National Institutes of Health NIDDK Cell Metabolism

Incredible tour de force by the amazing Alicia Chagoya shows the value of TOPMed imputation in Latino cohorts. Thanks to all co-authors, Philip Schroeder, Ravi Mandla, Joanne B. Cole Miriam Udler Lukasz Szczerbinski Vicky Kaur Alisa Manning Jose Florez Aaron Leong and many more!

The fact there’s a 99.9% chance the Big Ten commissioner will have to hand Jim Harbaugh the trophy is peak television

Shining in Maize and Blue until 2AM in honor of Michigan Football’s College Football Playoff National Championship

Go Blue!! National champs 🙂

Listen to my colleague and friend Veera Rajagopal  discuss recent GWAS findings on the genetic podcast. Fascinating stuff and, as always, well done!!