We polled: is a sulfilimine bio-isosteric for a sulfoxide? To test, we needed a late-stage S-imination method, now at: onlinelibrary.wiley.com/doi/10.1002/an…. Answer: S=NH is bio-isosteric, but depends. UBC Chemistry, #sulfur , #phosphorus , #Synthetic , #MedicinalChemistry , #methods , #peptides