Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells | Science science.org/doi/10.1126/sc…

Channeling antigens to CD8+ T cells | Science science.org/doi/10.1126/sc…

Perspective on a remarkable study by Patrycja Kozik exploring how Perforin-2 facilitates cell-associated Ag translocation from phagosome-to-cytosol in cDC1 cells. Kavita Rawat Channeling antigens to CD8+ T cells | Science science.org/doi/10.1126/sc…

Join us to work on dendritic cells, cross-presentation, and T cell priming @MRC_LMB - we have two postdoc positions available, deadline on Monday Sept 25th #CellBiology + #Immunology = 🥳 #PostdocJobs #AcademicTwitter

Elections time in Poland - fingers crossed 🤞 #wybory

How can lysosomes, when ruptured, maintain stability allowing for repair? Glad to share nature nature.com/articles/s4158… the function of stress granules (SG) as molecular plugs that stabilise damaged membranes The Francis Crick Institute Max Gutierrez #condensates #lysosomes #TB👇Thread

Many congratulations to Ellie Childs who defended her PhD thesis today. Well done Dr. Childs! Thank you very much to Dr Sophie Acton and Patrycja Kozik for acting as examiners!

Delighted to share our latest work, out in Nature Immunology, tackling the seemingly inordinate complexity of #cDC2s. Caetano Reis e Sousa The Francis Crick Institute, we found that distinct ontogenetic lineages dictate cDC2 heterogeneity, rather than cell states imposed by the tissue microenvironment 🧵(1/x)

Izzy will move to the LMB for a postdoc with Patrycja Kozik . While we’re sad to see Izzy go, we’re also excited to see where her career takes her. 🧫🧬🥼🧪👩‍🔬

⏰ Closing date to apply for a postdoc position in our lab is on Apr 14th - Join us @MRC_LMB to work on the molecular mechanisms involved in antigen presentation in dendritic cells! mrc.tal.net/vx/mobile-0/ap… #PostdocJobs #AcademicTwitter

Early-career researchers can now apply for a funded place at our Workshop "Immune Cell Interactions in Development, Homeostasis and Immunity" organised by Bousso Lab, @griffiths_lab, Sarris Lab & Michael Sixt ISTAustria Find out more and apply at bit.ly/4dNRIW1

Thrilled to share our newest study in Science Magazine. We created Boolean mice and CRISPR screened the heck outta ILC2s 🧵 1/ @MRC_LMB Wellcome Croucher Foundation

Early-career researchers - One month left to apply for a funded place at our Immune Cell Interactions in Development, Homeostasis and Immunity Workshop, organised Bousso Lab, @griffiths_lab, Sarris Lab & Michael Sixt ISTAustria biologists.com/workshops/febr… Deadline: 23 August

Postdoc position in dendritic cell and cross-presentation biology - four days left to apply: mrc.tal.net/vx/mobile-0/ap… Join our team to work on these coolest cells ever! 🥰

#ScienceSaturday Dendritic cells (DCs) play a critical role in activating CD4 and CD8 positive T cells to mediate the immune response against cancers. ❓But which DCs are the most important in triggering cancer-specific T cells? ➡️ In a recent report published in