Registration is open for the Advances in Antibacterial Discovery symposium on December 3rd. The virtual meeting is free to attend and I hope you will enjoy the science. bit.ly/3yNSz3b

The Role of Fatty Acid Metabolism in Drug Tolerance of Mycobacterium tuberculosis | mBio journals.asm.org/doi/10.1128/mb… The Eoh lab is glad to introduce the first paper of 2022.

Pandemic-related disruptions increased TB mortality for the first time in over a decade. @paimadhu, Tereza Kasaeva, and Soumya Swaminathan emphasize the need for digital tools and investments to detect and treat this disease, and get recovery back on track. bit.ly/3Aomwcx

There are couple of research associate and a Senior Project associate position available in the group. Interested candidates please apply. Details can be found at thsti.res.in Please spread the word. RT please. Thanks

Happy to share the "Dynamics of chromatin Map in TB patients". Interesting HDT candidates and TB biology. We found an unexpected role of potassium channel. Great collaboration with Shyam Prabhakar Lab nature.com/articles/s4156…

Superbug ‘pandemic’ stalks India as antibiotic resistance jumps 10% in a year. And “…By 2032, it is predicted that it will not be possible to treat 85 per cent of TB cases in India with common drugs”. telegraph.co.uk/global-health/…

Tuberculosis once again surpasses Covid as biggest infectious killer @TRTWorld trtworld.com/life/tuberculo…

Dynamics of resistance and tolerant population of M.tuberculosis. Intresting article mBio Origin and Dynamics of Mycobacterium tuberculosis Subpopulations That Predictably Generate Drug Tolerance and Resistance | mBio journals.asm.org/doi/10.1128/mb…

When you’re alone in the lab during the weekend

TB group at THSTI is looking forward to host this event. Please join. More details of the Symposium are available at thsti.in/tbconf/.

Excited to share our last review on the molecular basis and downstream immune consequences of mycobacteria-host cell interactions. Congrats to W Daher, J Karam and Virginia Pichler. Great discussions with Olivier Neyrolles. doi.org/10.1093/femsre…

•#Staphylococcus aureus activates #NLRP3 #inflammasome in macrophages •NLRP3 activation --> depletion of glucose in mac cytoplasm •Reduced glucose --> antibiotic tolerance in S. aureus •Restoration of cytoplasmic glucose improves antibiotic efficacy cell.com/iscience/fullt…

Elected to share our recent review published in NPJ Vaccines, in which we discuss "Antigen identification strategies and preclinical evaluation models for TB vaccines" coauthored with Ritika Kar Bahal(not on X). Thank you,Ramandeep Singh, for your support rdcu.be/dANbu

Really nice story on nutritional adaptation

Had an amazing time at the 3rd Annual Symposium: Innovations in anti-mycobacterial Drug Discovery. Got to see some biggest brains in the world of NTM and TB - seriously these folks probably dream in molecular structures. Talks were fantastic@Thanks NTU Singapore

CRISPRi-Tn-Seq! Great collaboration with @tvanop nature.com/articles/s4156…

Had an awesome time BacPath 17 in the past few days catching up with old friends and meeting new ones! We've got strong SG participation - Filloux lab Kimberly Kline 🏔 Cynthia Whitchurch, Laura Nolan & Peiyi Choo SCELSE and Manitosh Pandey from Stefan Oehlers! Future Bacpath in SG??

Day 3 #EMBOtuberculosis EMBO Heterogenity of lung granuloma, B cells, T cells, monocytes, AEC2, neuroimmune aspect Olivier Neyrolles Stefan Oehlers Simone Joosten LUMC Leiden Trude Helen Flo Reto Guler Rachit Agarwal and several amazing posters 👏🎊🥳👍

Day 4 #EMBOtuberculosis EMBO We discussed heterogenous nature of trained immunity, cell death, Mtb biofilms, lipid bodies, Mtb phenotype and drug discovery avenues +++ Maziar Divangahi Mehrotra Parul Ashwani Kumar CSIR-IMTech sheetalgandotra Priscille Brodin VaradhaLab_NCBS

We come to the end of #EMBOtuberculosis EMBO A*STAR Infectious Diseases (ID) Labs ICGEB, New Delhi CCMB What a faboulous 4 day TB-Mahakumbh, discussing excelent science 14 sessions, 46 talks & 115 posters. Proud of Sakshi Agarwal of getting one of the best poster award 🥳🎊👏