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Our latest work establishes that physical confinement directly regulates 3D colony growth by selectively favouring specific bacterial shapes 🦠 Read on to find out how 🏈 and ⚽ can have dramatically different outcomes under such regimes!

Writing this was a fun and highly involved learning process!

#Hiring Post-doc position available Tapomoy Bhattacharjee lab. Check out details 👇

Thanks for the lovely opportunity Living Machines-NCBS! Had an immensely fun session discussing the marvels of bacterial motion with this bright young cohort at the #PhysicsofLife2024 monsoon school.

Sreepadmanabh M was so kind to talk to us after the session about the exciting work he's doing and also showed us some of the gels he's prepared :) Thank you, Sree! Living Machines-NCBS Vaibhav Anand Hemanya Radadia

#Hiring Project Associate position available at our ESoftBio Lab ( Tapa Lab @NCBS ) lab National Centre for Biological Sciences. Check out details 👇

Sree Sreepadmanabh M will be presenting our work on bacterial growth under 3D confinement from National Centre for Biological Sciences in the PhD café (bit.ly/PhDCafe) series, organized by IndiaBioscience.org at 4 PM (IST) this Tuesday! Zoom: buff.ly/3XHewkk Youtube: tinyurl.com/Phdcafe

#CampusVisit MSc Microbiology students from Goa University recently had an insightful campus visit! They visited the labs RajLab_NCBS, CAPS NCBS and ESoftBio Lab ( Tapa Lab @NCBS ) and gained insights into computational protein science, developmental mechanisms and bioengineering.

Latest from our team 🥳 Had a lot of fun (and some lovely surprises!) with these experiments - simulating wound healing within precisely defined constraints. Check out the 🧵👇🏽 to see how we identified geometrical limits governing gap closure in epithelial monolayers.

We are thrilled to see our paper featured in Nature Communications as an Editors' Highlight! ESoftBio Lab ( Tapa Lab @NCBS ) National Centre for Biological Sciences The collection showcases the 50 best recent papers published in the area of Microbiology and Infectious Diseases! Read more: nature.com/collections/je…

Congratulations Sreepadmanabh M for this very well deserved recognition!!

Sree Sreepadmanabh M has received the 'Prof. Obaid Siddiqi Prize for Best Paper, 2024' by the Central Imaging and Flow Cytometry Facility at Bangalore Life Science Cluster (BLiSC) for his work on bacterial growth in 3D. Congratulations Sree! Read here: tinyurl.com/mvbdm3ue National Centre for Biological Sciences C-CAMP

Our latest piece - a remarkable example of how confinement regulates undulatory 🪱 motion! Combining experiments and theory on worms in 3D systems, we establish how an yield stress-dependent gait transition enables highly efficient propulsion. Check out the 🧵 below:

#Congratulations! 🎉 🏆 Sreepadmanabh M and Avik Pal are co-winners of the "Professor Obaid Siddiqi Best Paper Award 2024" awarded by the Central Imaging and Flow Cytometry Facility (CIFF) at BLiSC. Read their work here: lnkd.in/gkJmAMHC lnkd.in/gnhV2WC

If you are attending American Physical Society March meeting 2025 next week in LA, please come to our talks. Would love to say hi and catch up. We have five exciting talks from our group. RTs are appreciated.

Do swing by the APS DSOFT desk to catch some striking visuals of how physical confinement acts as a selective pressure on bacterial colony growth in 3D! American Physical Society APS Division of Biological Physics

Had a wonderful time at the American Physical Society March Meet 2025! Lovely feedback from the community on our work exploring biophysical regulation of growth, motility, and morphology. And a special thanks to APS Division of Biological Physics's Travel Award for enabling this! National Centre for Biological Sciences ESoftBio Lab ( Tapa Lab @NCBS ) Tapomoy Bhattacharjee

How does cellular shape tip the scales during growth under 3D confinement? Tune in to see our microbial version of why 🏈 trumps ⚽! National Centre for Biological Sciences Tapomoy Bhattacharjee ESoftBio Lab ( Tapa Lab @NCBS )

Vpr is an enigmatic protein encoded by HIV-1. Today, we report PLOS Pathogens the mechanism of circular RNA upregulation by Vpr. Grateful to EMBO DBT/WT India Alliance ICMR Anusandhan National Research Foundation and LTMT for enabling us IISER Bhopal Ministry of Education. journals.plos.org/plospathogens/…