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New study in Nature Communications unveils the potential of NOS inhibition in sensitizing metaplastic breast cancer. Our #GelCount platform played a major role in counting the #mammosphere assays. #BreastCancer #CancerTherapy #researchtools #LabAutomation nature.com/articles/s4146…

New research on triple-negative breast cancer! CD-44 nanoparticles show promise in combination therapy with high therapeutic efficacy and reduced tumor growth. The #HypoxyLab was used to mimic low O2 conditions #Nanoparticle #BreastCancer #CancerResearch sciencedirect.com/science/articl…

New insights into cerebral perfusion during cardiac arrest! 3-min vs. 5-min epinephrine intervals: higher pressure with 3-min but no blood flow difference. Our #OxyFlo measured the cerebral microvascular flow. Read here: sciencedirect.com/science/articl… #CardiacArrest #ResearchTools

Recreate in vivo oxygen conditions in your cell culture! Our guide explores: - #Physoxia vs. #hypoxia in research - Best practices for oxygen control - Tools like #HypoxyLab for precise environments Boost the relevance of your experiments! Learn more: oxford-optronix.com/resources/simu…

Breakthrough for oesophageal adenocarcinoma: New Scientific Reports study by a Queen's University Belfast 🎓 group shows dual inhibition of AKT + IAPs boosts chemo efficacy + overcomes resistance in organoids. #GelCount used for precise analysis. #CancerResearch Read more: nature.com/articles/s4159…

How did #flatworms adapt to life on land? 🌍🐛 New preprint reveals a burst of gene gain & unique stress responses in terrestrial species. Using #HypoxyLab, scientists uncovered key adaptations to oxygen changes. Read more: biorxiv.org/content/10.110… #Genomics #Evolution #hypoxia

New study in Journal of Physiology shows how the brain regulates blood pressure! Intracranial baroreceptors respond to pressure changes, triggering BP increases to maintain #cerebral flow. Using #OxyLite, the team showed pO2 dips were minimal, ruling out hypoxia. physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

Most cell cultures live in hyperoxia—far from physiological conditions. Why does this matter? #Hypoxia/#physoxia modeling is key for cancer, stem cell, and disease research. This paper explains the science and solutions. #CellCulture #TranslationalScience oxford-optronix.com/resources/what…

NIR-II photoacoustic imaging cuts tissue oxygenation error by 50% over NIR-l. The study was validated with our gold standard #OxyLite sensors for direct and precise pO₂ monitoring in a phantom model. #Biomedical #MedTech #PhotoacousticImaging #NIR pmc.ncbi.nlm.nih.gov/articles/PMC11…

New study: α1-adrenergic receptors don’t limit fetal cerebral blood flow during hypoxia, even at high altitude. #OxyLite/#OxyFlo sensors tracked pO₂ & flow in fetal lambs. Key for perinatal research! journals.physiology.org/doi/abs/10.115… #Neonatology #BiomedTech #CerebrovascularResearch

Ensuring sterility in hypoxia chambers is crucial. Our whitepaper covers best practices & how the #HypoxyLab system uses HEPA filtration, UV sterilization & smart design to minimize contamination risks. Read more: oxford-optronix.com/resources/cont… #ContaminationControl #HypoxiaResearch

New study in #Biomedicine: Combining #TemporalFractionation & #SpatialFractionation in #MRT boosts normal lung cell survival while keeping tumor kill effective in lung cancer models. #GelCount counts enabled precise survival curves. #CancerResearch doi.org/10.3390/biomed…

The compact hypoxy station, #HypoxyLab has a Smart Letterbox featuring an airlock so fast, your cells will feel like pampered VIPs!

It's the little things in cell research that make a big difference—humidity is often overlooked in hypoxia chambers. Learn how active humidification boosts reproducibility & cell viability: oxford-optronix.com/resources/acti… #CellResearch #Hypoxia #LabTech #Reproducibility #LifeSciences

For teams needing assurance their workstation is completely free of any contamination - Oxford Optronix is thrilled to announce MycoFog, a convenient bio-decontamination device for use in our widely trusted HypoxyLab cell culture workstation. Read more: oxford-optronix.com/news-events/in…

New Nature study shows hypoxia ↑ colorectal cancer stemness & chemo resistance. HypoxyLab was used to enable precise low-O2 conditions, validating stem cell markers (OCT4/NANOG). Key for CRC models. Read here: nature.com/articles/s4142… #CancerResearch #Hypoxia #DrugResistance

HIF-1α’s dual role in acrolein lung damage revealed! Study shows hypoxia (1% O₂) via #HypoxyLab lets HIF-1α either worsen or protect cells, depending on exposure. Key for understanding smoke/pollution toxicity! #LungHealth #EnvironmentalToxins 👉pubmed.ncbi.nlm.nih.gov/40252947/

A SCN1A mutation causes lethal apnea via brainstem depolarization. #OxyLite pO2 data showed medullary hypoxia follows depolarization, proving apnea happens before hypoxia. Implications for SIDS & migraine research. #Neuroscience #Genetics #Apnea pnas.org/doi/10.1073/pn…

ITPP cuts mortality in pulmonary hypertension in rats by tackling RV hypoxia. Real-time #OxyLite measurements showed RV pO₂ halved in PH (15 vs. 31.5 mmHg). ITPP restored pO₂ to 22 mmHg, improving survival outcomes. #PH #HeartResearch #hypoxia bpspubs.onlinelibrary.wiley.com/doi/10.1111/bp…