Can one self-assemble containers the size of cells using a single DNA origami? Well, now we can. Check out our preprint, where we present the underlying Dipid (DNA origami inspired by lipids) framework(biorxiv.org/content/10.110…). (TEM image of a collapsed container)

Spacer-Programmed Two-Dimensional DNA Origami Assembly | Journal of the American Chemical Society @CHNSci #2D #DNA #Origami #Assembly pubs.acs.org/doi/10.1021/ja…

Bending Unwinds DNA biorxiv.org/cgi/content/sh… #bioRxiv

A combined experiment and simulation (oxDNA + all-atom) preprint on how bending leads to DNA unwinding. doi.org/10.1101/2024.0…

Featuring oxDNA simulations to characterize the DNA tetrahedra: doi.org/10.1002/smll.2…

A paper in Nanoscale journal family featuring oxDNA simulations of the mechanisms of hybridization on DNA-coated gold nanoparticles: doi.org/10.1039/D3NR06…

Activationless Electron Transfer of Redox-DNA in Electrochemical Nanogaps | Journal of the American Chemical Society CNRS 🌍 Université Paris Cité UTokyo | 東京大学 #ElectronTransfer #RedoxDNA #Nanogaps #Electrochemistry pubs.acs.org/doi/10.1021/ja…

Featuring oxDNA simulations to characterize the DNA origami: doi.org/10.1021/jacs.3…

Featuring simulations with the oxDNA model to characterize electrode-tethered redox-DNA systems: doi.org/10.1021/jacs.3…

Featuring a little bit of oxDNA to characterize the DNA origami units: doi.org/10.1101/2024.0…

Our new model for DNA and RNA coarse-grained simulations is now out in The Journal of Chemical Physics : doi.org/10.1063/5.0199… It is called #oxNA and includes oxDNA and oxRNA and #oxRNA models, and adds support for hybrid DNA:RNA duplexes: 🧵1/4

Our new paper "Inverse design of a pyrochlore lattice of DNA origami through model-driven experiments" is just out in Science Magazine ! We use multiscale modeling and optimization theory to realize one of the main goals of colloidal self-assembly, the pyrochlore lattice.🧵1/7:

Our oxDNA and oxRNA /oxRNA models are still not fast enough to capture the timescales of bulk self assembly or large nanostructure folding.A new model (ANNaMO) developed with F.Guerra,@lrovigatti,floppleton.bsky.social is a step towards more coarse representations of DNA/RNA doi.org/10.1063/5.0202…

Here it is, the first bond that strengthens under stress (Nature Chemistry). Excellent work by Martijn van Galen, Annemarie Bok and Taieesa Peshkovsky, in collaboration with Joris Sprakel green mechanobiology and Jasper van der Gucht! Wageningen U&R Physical Chemistry and Soft Matter - WUR ORC_WUR nature.com/articles/s4155…

8y in the making and out now. Very proud of this, in collaboration with Albada Lab, by fantastic phd student Martijn van Galen. We managed to engineer one of Nature’s most clever molecular mechanobiology tool from the bottom up: de novo-catch bonds…a 🧵 nature.com/articles/s4155…

Here we report the DNA Origami Tension Sensor (DOTS) & measure TCR-pMHC forces in cell-cell junctions! Forces measured using microscopy or flow cytometry! Emory Chemistry⁩ ⁦Yuesong Hu⁩ ⁦salaitalab⁩ ⁦Emory University⁩ nature.com/articles/s4156…

Featuring a bit of oxDNA to characterize the DNA origami nanoswitch.

Featuring oxDNA simulations of the catch-bond system: doi.org/10.1038/s41557…

Featuring a little bit of oxDNA to characterize the tension sensor: doi.org/10.1038/s41565…

Featuring a bit of oxDNA to characterize the origamis: doi.org/10.1038/s41557…