Insulinoma or non-insulinoma pancreatogenous hypoglycemia? A diagnostic dilemma | Journal of Surgical Case Reports | Oxford Academic academic.oup.com/jscr/article/2…

Polycystic Ovarian Syndrome: Role of Imaging in Diagnosis | RadioGraphics pubs.rsna.org/doi/full/10.11…

Testicular Cancer Survivors Face Health Risks From Low Testosterone onclive.com/conference-cov… via OncLive.com

Low testosterone levels prevalent among testicular cancer survivors goo.gl/hzgiUy

Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies ncbi.nlm.nih.gov/pmc/articles/P…

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Anaplastic Thyroid Carcinoma: Practice Essentials, Pathophysiology, Epidemiology emedicine.medscape.com/article/283165… via Medscape

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Q&A: Anaplastic thyroid cancer bit.ly/2OuG32N

A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors ... bmccancer.biomedcentral.com/articles/10.11…

Ovarian Cancer Clinical Presentation: History, Physical Examination emedicine.medscape.com/article/255771… via Medscape

Case Scenarios in Androgen Deficiency ncbi.nlm.nih.gov/pmc/articles/P…

Ovarian Cancer Workup: Approach Considerations, Screening, Tumor Markers emedicine.medscape.com/article/255771… via Medscape

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Testicular Cancer Workup: Approach Considerations, Imaging Studies, Procedures emedicine.medscape.com/article/279007… via Medscape

Cowden syndrome is associated with PTEN tumor suppressor gene known as phosphatase and tensin homolog. Dysregulates the mTOR pathway leading to errors in cell proliferation, cell cycling and apoptosis. Primarily a dermatologic condition.

Multi-system involvements are seen in cowden: macrocephaly with malignancy in the breast (adenocarcinoma (20%); thyroid adenocarcinoma (70%); squamons cell carcinomas and the remaining from uterus colon and others.

SDHB gene is associated with extraadrenal/malignant pheochromocytomas due to lack of enzyme involved in conversion of succinate of fumarate causing succinate accumulation inducing HIF protein leading to uncontrolled cell proliferations and tumors.