µPhos is a new #phosphoproteomics platform that allows for increased sensitivity and depth, over 90% selectivity, and great reproducibility. It quantifies over 20,000 unique #phosphopeptides in a human #cancer cell line using only 20 µg starting material: goto.bruker.com/3K4HVxQ

Looking forward to this event. Dense format, great lineup of speakers!

Do you want to push the boundaries of mass spectrometry-based phosphoproteomics and make a difference in virology? We have a 3-years PhD position available funded by DFG public | @[email protected] in collaboration with Systems Arbovirology. Please RT and reach out if interested.

Peptide collision cross sections of 22 post-translational modifications by Florian Meier et al Florian Meier Denys Oliinyk Uniklinik Jena Bleiholder Group FSU Chemistry & Biochemistry Florida State University #peptides #PTMs #OpenAccess link.springer.com/article/10.100…

Excited to see this exciting and thourough story, led by @A_Will_tweets, out in Anal Bioanal Chem! Check it out!

Our lab is hiring two Research Assistants. A Computer Scientist and a Biomedical Scientist. Please help us spread the word and apply before Nov. 29th.

And the big THANK YOU goes this time to Florian Meier and colleagues for this great cover! 🎉 @A_Will_tweets Florian Meier Denys Oliinyk Uniklinik Jena Bleiholder Group FSU Chemistry & Biochemistry Florida State University Read here their Paper in Forefront: link.springer.com/article/10.100…

Very excited to see this work on bioRxiv! In this fantastic collaborative effort with @russo__DA and Zedler Lab we achieve an unprecedented depth in analysis of cyanobacterial exoproteome! Find out more: dlvr.it/T3YMPX

📢 Open PhD positions! Do you want to work with leading researchers in academia and industry to unlock the full potential of Ion Mobility - Mass Spectrometry? 💡 Learn more: mobilitrain.eu ✍ Apply here: euraxess.ec.europa.eu/jobs/206785

What a great honor to receive the Am Soc for Mass Spec Graduate Student Award! A big thank you to Florian Meier and the whole group for the immense support, can’t wait to celebrate other recipients in June!

Thrilled to finally see µPhos published in Mol Syst Biol! A big thank you to Florian Meier, Sean Humphrey and all other coauthors for this exciting journey! Check out our greatly improved and extended story on how to unlock the true power of phosphoproteomics: embopress.org/doi/full/10.10…

Spectronaut solves many of the challenges of large-scale proteomics studies. #Spectronaut user Florian Meier (Uniklinik Jena) shares with us why Spectronaut is his software of choice for PTM studies at scale. Get in touch for a free trial: ow.ly/eI2O50SuCfp

Introducing @PulsPhos: our new method to quantify phosphorylation lifetimes in living cells. See how it reveals key protein dynamics! #Phosphoproteomics #CellBiology Yansheng Liu Pedro Beltrao Julian van Gerwen @[email protected] Nisha Hemandhar Kumar biorxiv.org/content/10.110…

Very nice to see the result of my internship at Genentech out in bioRxiv! If you’re intersted in diaPASEF and immunopeptidomics, check this out: biorxiv.org/content/10.110…. Big thanks to SKlaeger and Christopher Rose for introducing me to immunopeptidomics!

Finally out! EXCRETE, our MS workflow for high throughout microbial exoproteomics with a focus here on cyanobacteria 🦠 nature.com/articles/s4200…

Published today! Spatial proteomics reveals JAK/STAT as a target for Toxic Epidermal Necrolysis, an often fatal skin reaction to common medication. We validated our findings in pre-clinical models & successfully treated the first patients worldwide.🧵⬇️ nature.com/articles/s4158…

AATD affects thousands, causing liver & lung disease via protein aggregation. Our new preprint used #DeepVisualProteomics to study liver cells and reveals key AATD insights with clinical implications . Video and tweetorial Florian Rosenberger #Alpha1Awareness bit.ly/4hzl64o

To bead or not to bead? We evaluate five plasma proteomics workflows, finding bead-based methods enhance detection but show high susceptibility to cellular contamination bias. Strategies to optimize biomarker discovery in plasma proteomics. doi.org/10.1101/2025.0…

Nano-scale, mega-impact: nanoPhos delivers 100× phosphoproteomics sensitivity, 70k sites from 1µg, 8k from 10ng! Powered by SPEC, it enables phosphoDVP: deep spatial phosphoproteomics from 1000 neurons, hitting 17k sites, a game changer for spatial omics. biorxiv.org/content/10.110…

Protein digestion in 200 nL on solid-phase tips: SPEC enables low-input proteomics—even with SDS/SDC at high levels. From FFPE and muscle to high throughput plasma. SPEC is a universal and Evosep-compatible protocol. biorxiv.org/content/10.110…