It was fantastic to present our work on measuring the proliferation rates of distinct tumour clones using single-cell whole genome DNA sequencing data in #TRACERx & #PEACE at #AACR23! A huge thank you to my supervisors Charles Swanton Simone Zaccaria & funders Wellcome Cancer Research UK

Thrilled to present our work linking proliferation rate to the evolution of single-cell clones in #TRACERx and #PEACE at #AACRevol23! Thank you to Simone Zaccaria Charles Swanton @MariamJHanjani Nnennaya Kanu Cancer Research UK Wellcome UCL Cancer Institute CRUK Lung Centre The Breast Cancer Research Foundation and the Crick!

The complexity of #TNBC genomes- fantastic data by #breastcancer Charles Swanton FabriceAndre SABCS #sabcs23

SABCS @UTHealthSAMDA AACR Huge thanks to The Breast Cancer Research Foundation FabriceAndre @GroupeUnicancer Institut Curie The Francis Crick Institute UCL Cancer Institute CRUKCOLcentre Science and Innovation at Cancer Research UK Nnenna Kanu Monica Arnedos Christophe Le Tourneau @MariamJHanjani Ieva Osaite Olivia Lucas and Simone Zaccaria Chris Bailey for making Breast TRACERx possible

Thank you CRUKCOLcentre for a fantastic conference!

Today is #WorldCancerDay and City of London Centre is proud to support the future leaders in cancer research by giving them a stage to shine in this week’s Centre symposium. All speakers are early career researchers and thank you for your excellent talks. colcc.ac.uk/events/

Our radiographers have scanned nearly 6,000 people since December 2022 as part of a lung health check. They are helping to improve early #cancer diagnosis in North Central London. Find out more about lung health checks here: buff.ly/3HLzvd8 #WorldCancerDay2024

📢📢 We're hiring! Just finished your PhD? Come help us figure out how cancers evolve and develop diagnostics. You'll work in a multi-lab team Early Cancer Institute, University of Cambridge/The Crick and lead a stunning project on lung cancer. Flexible start date to Oct. Pls RT! jobs.cam.ac.uk/job/45357/

🙏to Science and Innovation at Cancer Research UK Rosetrees Trust we study which where when cancer cells metastasise All led by huge talents Olivia Lucas Rija Zaidi Sophie Ward Abi Bunkum Lucrezia Patruno others in #TRACERx #PEACE with Charles Swanton @MariamJHanjani Nicholas McGranahan Many results to share soon👇

Tim Elliott, Kevin Litchfield, Sarah Blagden, Mariam Jamal-Hanjani and Maise Albakir will use a Biology to Prevention Award, joint with the CRIS Cancer Foundation, to develop a novel vaccine to prevent #LungCancer by targeting hotspot neoantigens via the ChAdOx platform.

1 in 2 people will get cancer in their lifetime. Our CCG Lab at UCL Cancer Institute'll run Cancer Research UK Muddy Race this May to highlight the importance of funding cancer research Science and Innovation at Cancer Research UK and improving patient outcomes. Please support us if you can! #RaceforLife 👉fundraise.cancerresearchuk.org/team/ccg-lab

Fantastic to present our work on understanding the role of clone proliferation in cancer evolution at the Crick Clinical Research Fellows Meeting today! A very informative and enjoyable day. Thank you Charles Swanton Simone Zaccaria Cancer Research UK Wellcome UCL Cancer Institute The Breast Cancer Research Foundation

Thrilled to receive a clinical fellows poster prize today at the UCL Clinical Academics Trainee Symposium for our work on cancer clone proliferation & its potential clinical relevance! Thanks Charles Swanton Simone Zaccaria UCL Academic Careers Office Cancer Research UK Wellcome UCL Cancer Institute The Breast Cancer Research Foundation The Francis Crick Institute

As a proud Science and Innovation at Cancer Research UK funded lab Computational Cancer Genomics (CCG) Research Group, we ran the Cancer Research UK Pretty Muddy #RaceforLife ! See before vs after 👇 Couldn't be prouder of our wonderful team! Follow their journeys: Sonya Hessey Jeanette Kittel Rija Zaidi Abi Bunkum Lucrezia Patruno Olivia Lucas

Why do some patients benefit less than others from precision cancer medicine? We are excited to share our paper "Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling” out in Nature Communications. nature.com/articles/s4146… 🧵

Fantastic to present and receive 1st poster prize today at the UCL Cancer Institute Annual Conference for our work on clone proliferation in cancer evolution with the SPRINTER algorithm! Huge thanks to the team Charles Swanton Simone Zaccaria UCL Cancer Institute Cancer Research UK Wellcome The Breast Cancer Research Foundation The Francis Crick Institute

Today our study of the association between replication timing alterations and mutation acquisition during cancer evolution has been published in Nature Communications nature.com/articles/s4146…

It was such a pleasure for Olivia Lucas and me to help with this very important study from Nnennaya Kanu Nicholas McGranahan Charles Swanton splendidly led by Michelle Dietzen Haoran Zhai Replication timing is key in cancer and can teach us so much more about tumour evolutionary history👇

So proud that our paper introducing SPRINTER to characterise clone proliferation through cancer evolution is out in Nature Genetics!