One of the biggest studies of dietary restrictions ever conducted in laboratory animals challenges the conventional wisdom about how dietary restriction boosts longevity go.nature.com/3NieZDy

Congrats to the whole Mackay Lab team on this seminal discovery and excited to have Andreas Obers join us next feb for his postdoc in #Naiklab

How does #RetinoicAcid (RA) affect immunosurveillance? Andreas Obers (Andreas Obers), @MaxEvrard, & Laura Mackay (Mackay Lab) showed that RA mediates tissue-resident memory T cell maintenance by limiting retrograde migration. 💬 bit.ly/4fxHaL1 x.com/LMackayLab/sta…

Guess what? Mitochondria are weirder than we thought

Nature research paper: Cellular ATP demand creates metabolically distinct subpopulations of mitochondria nature.com/articles/s4158…

How do mitochondria, the cell’s energy-producing organelles, perform competing metabolic processes? Segregation into distinct populations — one that makes energy-storing ATP molecules and one that does not — could explain it nature.com/articles/d4158…

🧬 New research led by Andreas Obers Maximilien Evrard Mackay Lab reveals that retinoic acid, derived from vitamin A, guides disease-fighting T cells to organs like the gut & liver—paving the way for future therapies! 🔗go.unimelb.edu.au/2o98 UniMelb MDHS The Royal Melbourne Hospital

Diet, commensals, and host factors determine TRM cell development, maintenance, and function across tissues Immunity Elina I. Zúñiga cell.com/immunity/fullt… cell.com/immunity/fullt… cell.com/immunity/fullt… Maximilien Evrard Hongbo Chi Jana Raynor Andreas Obers Mackay Lab

Over the moon to be named among the #50ScientistsThatInspire across diverse fields by Cell! A heartfelt thank you to my former and current lab members, mentors, collaborators, and friends—you are my daily inspiration! cell.com/news-do/50-ins…

Today we report Evo, a generalist foundation model for biology, on the cover of Science Magazine. Trained on billions of DNA nucleotides, Evo was designed to capture two key aspects of biology: the multi-modality of the central dogma and the multi-scale nature of evolution.

Comment l Stefan Jordan and colleagues from the C3R Wildling HeaD consortium share their experience designing a facility for safe and ethical research with Wildling mice Charité - Universitätsmedizin Berlin JordanLab Stephan P. Rosshart DiefenbachLab Link 👉 nature.com/articles/s4168…

Home at last: Mixed signals guide memory T cells to residency dlvr.it/TGCwDh

Nature research paper: Adipose tissue retains an epigenetic memory of obesity after weight loss go.nature.com/4eJizC8

Thrilled to share the results of our 8-year-long expedition into the Wild, the city of #NYC , the wild west of #LosAngelesCA , and more—in search of the roots of gut fungal commensalism! 🧵nature.com/articles/s4158…

Misinformation is winning not because it's true, but because it’s loud, emotional, and everywhere. It’s time for science to fight back. Aaron Mertz and I dissect the issue and offer solutions 👇 📖 nature.com/articles/s4157… #SciComm Nature Rev Immunol The Aspen Institute Icahn School of Medicine at Mount Sinai

A new Yale study shows for the first time that immune-system T cells are present in the brain, sent by the gut to a region that regulates hunger and thirst — a finding about T-cell physiology “that changes everything,” says one researcher: bit.ly/4mB9O1Q #Yale

Interested in Inflammatory Memory? Want to learn more about a seminal paper that redefined our understanding of immunology? Check out Dr. Shruti Naik and I’s Pillars of Immunology article on Foster, Hargreaves, and Medzhitov’s landmark 2007 Nature study doi.org/10.1093/jimmun…

Congrats to superstar Asma Farhat for being selected as a Simons Postdoctoral fellow to study how inflammation impacts sensory development and function in the Naik lab and the Allen Discovery Center. Simons Foundation Lipschultz Precision Immunology Institute Friedman Brain Institute simonsfoundation.org/people/asma-fa…