🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Exciting opportunity to start your own research group with a #Parkinson's disease research focus as Safra fellow at Imperial Medicine: imperial.ac.uk/jobs/search-jo… Deadline: 16 Feb I started my own group on this fellowship 5 years ago, so if you have any questions, get in touch!

In a big life update, I successfully defended my PhD thesis - massive thanks to my PI Nathan Skene and assessors @steinaerts and Tom Ellis. Also thrilled to share that I will be joining Peter Koo at CSHL in the new year for a post-doc improving genomic deep learning models!

Just in time for the holidays, we are thrilled to give you the latest preprint from our lab: Unique nigral and cortical pathways implicated by epigenomic and transcriptional analyses in a rotenone rat model of Parkinson's disease doi.org/10.1101/2024.1…

🚨 Check out our latest contribution where we delve into the dementia-related snRNA-seq data and spotlight the signature changes in brain #endothelialcells and #pericytes! Very proud of the effort led by Dr. Michael Sewell and Nela Fialova Nela Fialova. alz-journals.onlinelibrary.wiley.com/doi/full/10.10…

📢 Our lab is looking for a bioinformatics postdoc. We have lots of exciting projects to work on, including single cell data, microglia xenotransplantations and nanopore long reads splicing analysis. Look out for the official advert next week and get in touch in the meantime 🧬🧠

Are you looking for a fully funded #PhD studentship? Join our Dr Nurun Fancy for a studentship for 3.5 year project investigating the role of LRRK2 in cellular senescence in Parkinson’s Disease. Find out more👇 imperial.ac.uk/brain-sciences…

Last day UK Dementia Research Institute Imperial Department of Brain Sciences before starting my maternity leave 🍼 I will only briefly come back before heading to Turin for a new adventure Marie Skłodowska-Curie Actions 🇮🇹Millions thanks to this bunch of people who supported me through these last 4 intense years! 💙🙏

The advert is officially live and you can apply online here: tinyurl.com/yd5bsvfb

Exciting new role for a Computational Genomics Research Associate in the lab of Sarah Marzi at the UK DRI at King's! Lead projects exploring the epigenome and transcriptome of brain cells in neurodegenerative diseases 🧠 🗓️Deadline: 08 March Full info👉 shorturl.at/fk7jS

Thank you to UK Dementia Research Institute Group Leader Alexi Nott 🏳️‍🌈 for joining us today & for his great talk on ‘The Epigenome of brain cell types and associations with disease’ Kavli Institute for Nanoscience Discovery, Oxford Department of Physiology Anatomy & Genetics (DPAG) Sophie L. Farrow

The Dept. of Brain Sciences at Imperial (Imperial Department of Brain Sciences) is recruiting a new Head of Department (link below). Keen to have someone great take the role, and come and work with us! Please pass onto anyone that might be interested

We're so thrilled to finally share with you the published version of our CUT&Tag optimization and benchmarking paper "CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks" - out in Nature Communications today: nature.com/articles/s4146…

Alexi Nott 🏳️‍🌈 we are looking forward to your presentation at #Neuroepi25 in Malta.🌞 Please share with your followers to let them know early bird registration & talk submission closes on 24 April 2025! Find out more: bit.ly/42ls1an #FusionNeuro

Wonderful evening with Shane Liddelow following his visit to Imperial Department of Brain Sciences UK Dementia Research Institute 🧠

We are so happy to share our latest paper "CHAS infers cell type-specific signatures in bulk brain acetylation studies of neurological and psychiatric disorders". cell.com/cell-reports-m… UK Dementia Research Institute Institute of Psychiatry, Psychology & Neuroscience Imperial Medicine

A first first-author paper by Aydan Askarova with Reuben Yaa & Sarah Marzi showing that genetic risk for neurodegenerative conditions is linked to disease-specific microglial pathways 🎉📷 journals.plos.org/plosgenetics/a…… More to come from Aydan later (hopefully) this year...

Really nice work from the Alexi Nott 🏳️‍🌈 lab using functional genomics to show that genetic risk for multiple neurodegenerative diseases is linked to disease-specific microglial pathways. Congrats Aydan, Reuben and Alexi 👏🏻✨

Trying to get cell type specific insights from bulk brain epigenetic studies? Check out our new method CHAS for cell type deconvolution in brain studies of histone acetylation. Reanalysis of bulk data from >300 samples revealed novel cell type specific epigenetic associations👇🏻

Dear immune/glia lovers of brain, gut and beyond… We’re looking for a lab tech/manager to join our team! Pls see details for application here ucl.ac.uk/work-at-ucl/se… UK Dementia Research Institute UCL - pls help circulate among networks who’d be of interest, thank you!

How does APOE change your risk of developing Alzheimer's disease? At least partially by changing the function of immune cells in your brain 🧠🧬 New paper out in Nature Communications today : nature.com/articles/s4146… UK Dementia Research Institute Institute of Psychiatry, Psychology & Neuroscience Imperial Medicine VIB