Why do some triple negative breast cancer patients respond to anti-PD-L1/PD-1 immune checkpoint blockade, while others do not? We investigated this question nature.com/articles/s4146… Goga Lab @UCSFcancer #breastcancer Tweetorial 👇

Excited to share how #cancer cells can reprogram the resistance mechanisms similar to that of #bacteria. aacrjournals.org/cancerdiscover…

Now online in Cancer Discovery: AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat #EGFR-mutant #LungCancer by Ashish Noronha, Yosef Yarden, and colleagues Weizmann Institute aacrjournals.org/cancerdiscover…

From the November issue: AXL and Error-Prone #DNAReplication Confer Drug Resistance and Offer Strategies to Treat #EGFR-mutant #LungCancer, by Ashish Noronha, Yosef Yarden et al. bit.ly/3ihq8It Weizmann Institute

A single-cell analysis of tumor-infiltrating T cells from 16 cancer types identifies new T cell subsets and a stress response cell state enriched in tumors resistant to immunotherapy. nature.com/articles/s4159…

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways | Nature Communications nature.com/articles/s4146…