🔬 How's AI transforming biology? 📡 FM4Bio Seminar Series—exploring how foundation models simulate, predict & program life (DNA → cells). 🧬 Join top AI + bio researchers. 👉 x.genbio.ai/x-seminar

Engineered implementations of spatial computation in biological systems doi.org/10.1016/j.semc…

A VISUAL GUIDE TO GENE DELIVERY There are at least 10,000 known monogenic diseases. Many scientists are trying to build gene therapies to cure some of them. Learn about tradeoffs between the various delivery options—from AAV to LNPs to Herpes Virus—in our latest article.

That's cute, the PI actually attends the meeting

Fun fact: In 2016 "The coming of age of de novo protein design" was a key review of the progress in de novo design. 8yrs later "Sparks of function by de novo protein design" (as a reference to GPT4📝) can be considered its spiritual successor in the era of AI-based protein design

Out Now! Deep, long-read metagenome sequencing expands knowledge of prokaryotic phylogenetic diversity bit.ly/4ogq3lL #Metagenomics #MicrobialDiversity #Phylogenetics

My view is that grant and facility peer review needs to be prioritised over journal peer review. If we stop peer reviewing proposals then we’re in a lot more trouble than if we stop reviewing papers, which really should all be preprinted already in today’s science.

The best phage!

New paper from our lab on synthetic genome work in yeast is out - Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes. Exciting project led by Jane (Xinyu) Lu in our group, now online Nature Communications nature.com/articles/s4146…

Dynamic Tuning of Genetic Circuit Gain via Controllable Plasmid Copy Number biorxiv.org/content/10.110… #biorxiv_synbio

Busy busy busy busy busy

Protein designers have long dreamed of building new enzymes from scratch. Unfortunately, enzymes are highly dynamic; they move around a lot and have intermediate states that are difficult to design computationally. But a recent paper from David Baker’s group at the Institute

You: should I cite my paper? Maybe it's not related enough? Ok, screw it, I'll self-cite but only once. Other scientists: With AI, I can cite myself 1.3M times 😎

Out Now! A defined microbial community reproduces attributes of fine flavour chocolate fermentation bit.ly/4mlEnIi #Microbiology #ChocolateFermentation #FineChocolate

Out Now! Amyloids in bacterial antiphage defence bit.ly/3UFCKJu #Amyloids #BacterialDefense #PhageInfection

Only a small bit of sunlight is used to "power" photosynthesis. Roughly half of all sunlight that reaches Earth is absorbed or reflected by the atmosphere. Another 9,000,000 GW (~15 percent of the light reaching the ground) is reflected back into space.

SUPER COOL, I hope not dangerous...?

genome mining tool searches for colocalized homologs of any marker genes/proteins lab111.mbu.cas.cz/cluseek/

Leaving the lab to this encounter. Is this a good omen?

SDSが析出するようになると秋の訪れを感じます。 昨晩の最低気温は13.9℃だったそうです。