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https://orip.nih.gov 19-07-2016 18:45:36
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Researchers study how nutrient stress leads to upregulation of a cancer stem cell marker, integrin αvβ3, which promotes metabolic plasticity in lung cancer cells. Nam et al. UC San Diego Health NINDS National Cancer Institute NIGMS (ORIP support through K01OD030513) pubmed.ncbi.nlm.nih.gov/38588407/
⌚️Researchers discover different sample collection times can lead to different conclusions in microbiome studies. Allaband et al., @NIAIDnews, NIH NHLBI, National Cancer Institute, NIDDK, NCATS, NIAAA News UCSD Biomed Sciences PhD Program (ORIP support through T32OD017863) pubmed.ncbi.nlm.nih.gov/38951660/
👀READ: “A germ-free humanized mouse model shows the contribution of resident microbiota to human-specific pathogen infection.” Wahl et al., National Cancer Institute NIAID News NIDDK (ORIP support through P40OD010995) ncbi.nlm.nih.gov/pmc/articles/P…
🐒Researchers demonstrate successful genome editing in the lungs of young rhesus monkeys using AAV5. Liang et al., RNA Therapeutics Institute Koch Institute at MIT NIH NHLBI, National Cancer Institute, NIGMS (ORIP support through U42OD027094, P51OD011107, S10RR025063 & S10OD028713) pubmed.ncbi.nlm.nih.gov/38767512/
A thank you for your thank you😊The scholars participating in the K-StateVetMed Veterinary Research Scholars Program this summer expressed their appreciation for the support provided by #ORIP. We hope to continue encouraging veterinarians to pursue careers in biomedical research.
READ: “Evolution of the clinical-stage hyperactive TcBuster transposase as a platform for robust non-viral production of adoptive cellular therapies” Skeate et al., @NIAIDnews, National Cancer Institute, NIH NHLBI (ORIP support through F30OD030021, U24OD026641) pubmed.ncbi.nlm.nih.gov/38627969/
🐭READ: “Deletion of mouse lysyl oxidase in megakaryocytes affects bone properties in a sex-dependent manner” Karagianni et al., Boston University Center for Musculoskeletal Research (ORIP support through K01OD025290) #sciencetwitter pubmed.ncbi.nlm.nih.gov/38635757/
CRISPR-Cas technology has transformed our ability to introduce targeted modifications allowing animal models like pigs to model human diseases thus, is critical to ID off-targeting modifications in their genomes. Agricultural Research Service Mizzou CAFNR (ORIP support-R01OD035561) pubmed.ncbi.nlm.nih.gov/38770737/
Tomorrow🗓️Session I of the Cryopreservation & Other Preservation Approaches for Animal Models Workshop is taking place from 10am-4pm EDT. The session will feature talks on invertebrate models. NIGMS NICHD News Genetics Society of America Society for Cryobiology Register today: scgcorp.com/Cryopreservati…
Scientists gain important insights through mechanical and morphometric approaches to body mass estimation in rhesus macaques: using skeletal features for accuracy. Turcotte et al., Caribbean Primate Research Center CSHO @ NYU NYCEP (ORIP support through P40OD012217) pubmed.ncbi.nlm.nih.gov/38445298/