GATK is one of the most-used apps on #Biowulf. Learn how to use GATK4 for your genomic variant analyses--and efficiently on the cluster!--in our new tutorial hpc.nih.gov/training/gatk_… GATK Dev Team NIH Intramural

A great example of how #NIH's #Biowulf #supercomputer has assisted with #COVID19 research NIH HPC

Andy Baxevanis ➜ @baxevanislab.bsky.social National Human Genome Research Institute Thanks Andy! And mark this down as another NIH HPC success story. All the assemblies ran there and the whole consortium relied on our Globus share, all during a pandemic. Hats off to them!

Congratz to Adam Phillippy and his #NIH National Human Genome Research Institute team, as well as their collaborators in the #T2T consortium, on this huge achievement! And, of course, the team at NIH HPC, who run the Biowulf #supercomputer that leant its massive computational power to this effort!

Congratulations!

Curious how #NIH researchers are utilizing NIH HPC's #Biowulf #supercomputer in their research? Visit the "I Am Intramural" #blog to learn about one such study that could help lead to a medication that reduces the side effects of #cancer #chemotherapy: go.usa.gov/xueNR

Using network storage for temp files is like making a new trip to the store for each ingredient in your sandwich. Reduce traffic 🚦. Use local scratch instead. hpc.nih.gov/docs/userguide… #TipTuesday

The user dashboard is your #Biowulf control room. See and request changes to your groups and disk quotas. Monitor your jobs and resource utilization. hpc.nih.gov/dashboard #TipTuesday

Your #biowulf job is coming up on its walltime limit, but it's not done yet 😬 What do you do? Use newwall to extend your walltime*! #TipTuesday *up to the partition time limit. other restrictions apply. see hpc.nih.gov/docs/userguide… for details

There are now 5000 papers #PoweredByBiowulf! 🥳 We're proud to support the NIH Intramural with this essential resource and looking forward to enabling many more papers to come. ☺️

Impressive! To learn about some of the ways that #NIH #COVID19 research in particular has been #PoweredByBiowulf, check out this piece on our "I Am Intramural" #blog: irp.nih.gov/blog/post/2020…

Do you have short ( < 4 hr) jobs that you want to start quickly on #Biowulf? Consider submitting to the 'quick' partition to get priority scheduling. #TipTuesday

You: I have a lot of samples to process. I’ll just run sbatch out of a for-loop, and then I— Us: No! Use a job array. Or even better, use swarm on #Biowulf. hpc.nih.gov/apps/swarm.html #TipTuesday #hpctips

If you have a lot of short (<5min) jobs, bundle them up to get a bulk discount on your scheduling time. swarm's --bundle option will group them into bundles & run each bundled command in succession within a single subjob. See hpc.nih.gov/apps/swarm.htm… #TipTuesday #hpctips

Be careful about loading modules and activating conda environments in your bashrc. It's nice to have all your tools at your fingertips when you log in, but they don't always integrate well with each other. Load only what you need when you need it. #TipTuesday

Sofia Barreira from our lab National Human Genome Research Institute NIH Intramural presenting her work on the evolutionary history of the nucleolar transcription factor at #SICB2023... sequence meets structure! #AlphaFold #ProteinFolding @NIH_HPC #PoweredByBiowulf

Paul Gonzalez from our lab National Human Genome Research Institute NIH Intramural presenting his work on the evolution of non-coding elements associated with homeobox genes at #SICB2023 – an extremely computationally intensive study that wouldn't have been possible without being #PoweredByBiowulf! @NIH_HPC

When your pipelines generate HTML reports on #biowulf, you don't have to copy all the results back to your desktop to catch a glimpse. Use hpcdrive to locally mount your hpc storage and browse directly to it. hpc.nih.gov/docs/hpcdrive.… #TipTuesday

A nice history of CIT featuring some info and a baby picture of #Biowulf

Congratulations to both of them-- #Biowulf Power PIs!