mRNA vaccines in arms are saving lives. RNAs in our cells however exist in protein-coated RNPs. To capture RNA structure, w/ Steven Artandi, MD, PhD Howard Chang, our STAR Protocols analyzed native RNPs by icSHAPE combining genetic+biochemical reconstitutions.(1/2) sciencedirect.com/science/articl…

Our paper is out today!! We show that the E3 ligase RNF213 ubiquitylates lipopolysaccharide (LPS) on the bacterial surface during infection. This is the first example of ubiquitylation of a non-proteinaceous substrate. Find our article here: nature.com/articles/s4158… 1/10

“There’s no secret to it; my experience can be summed in four words: knowledge, sweat, inspiration and opportunity,” Mr. Yuan said in a video message last year encouraging young Chinese to go into science. nytimes.com/2021/05/23/obi…

Our latest manuscript is live! Postdoc Cori Cahoon developed and used the auxin degron system to conditionally immobilize #celegans for live imaging. Works efficiently in both hermaphrodite and male worms! Cori also found males need higher auxin levels. biorxiv.org/content/10.110…

Way to go! Dr. Ooi! Soon-Keat Ooi

It is with great sadness that we announce the passing of our co-founder, Virginia G. Stowers. We remain grateful for the vision of the Institute she and her husband Jim shared, and for the generous, ongoing support that is the legacy of their endowment. stowers.org/virginia-stowe…

biorxiv.org/content/10.110…

For 20 years, Joan & Ron Conaway have led a nationally recognized program at the Stowers Institute but this year they begin a journey down a new path, leaving Kansas City for their new home in Texas. They will be greatly missed at Stowers. ow.ly/2Ehh50FhYnE

“Children are born curious, with passion for questions and with light in their eyes. I hope the papers in this journal may help nurture and reinforce children’s passion and curiosity for science – what a gift to humanity that would be!” says May-Britt Moser at Kavli Neuroscience

Our story on functional interaction between the Mediator and enhancer is out. We show that one of the Pol II elongation factor-Elongin may function as a “loading factor” that regulates the transition of Mediator into a function PIC for ER stress genes. pnas.org/content/118/39…

Happy to share our recent work that reveals how epigenetic regulators KDM5B and SETDB1 promote immunoevasion in melanoma. m.yale.edu/p347 via @yalemed Yale Pathology Yale Cancer Center Yale Center for Immuno-Oncology

It’s Fauci's 81st birthday today. Let's wish him a good birthday and holiday! ☃️🎂🎄

We are excited to announce the next two months of Fragile Nucleosome seminars! We will kick off the series next week Jan 12th at 9AM PST. Hope to see you all there! Happy new year! Registration for seminar with Steve Buratowski & Samuel Corless: essex-university.zoom.us/webinar/regist…

The faculty in Yale Cell Biology and Yale Stem Cell Cente strongly support our colleague Haifan Lin and his entire research group in the wake of his administrative suspension by Yale University, a step taken without any formal charges or due process. See our statement 👇👇

Opening a new dropbox at Dana-Farber, shipping Tuesdays at 4pm. Located in the 1st floor lobby of the Mayer Building, by the elevators. Enter 440 Brookline Ave, or access the Mayer Building lobby from the Dana Building entrance (44 Binney St).

Our next seminar is Dec 7 @ 9AM PST, with 2 speakers! 1. Nitin Shirole (postdoc in the KaelinLab): HIF-alpha TFs in clear cell renal cell carcinoma 2. Tugba Bagci Onder (TBOLab): Epigenetic regulation of therapy response in cancer Register here: harvard.zoom.us/webinar/regist…

Join #ConnectScience on 4/25 at 12 EST: Speaker: michele pagano (NYU Langone Health) “Why Cells Degrade #CyclinD1 at G1/s? And How Do They Limit #DNAMismatchRepair in G1? Two Seemingly Unrelated Questions." Hosted by DF/HCC Postdoc: Nitin Shirole (Dana-Farber) dfhcc.harvard.edu/connectscience

#ChineseSpringFestival is a time to welcome the Year of the Dragon! And the #loong (Chinese dragon) is in town! But hold on a sec, here's another #Dragon from the West, and it seems like they're old buddies or something... Let the dragon drama unfold!

I’m sorry to share the sad news that Michael Grunstein, Distinguished Prof UCLA Biological Chemistry David Geffen School of Medicine at UCLA UCLA passed away early this morning after 20 yr battle with Parkinson’s disease. Condolences to friends & family 💐 This is my note to the department.