How can we use SPARQL to help deciphering the functions of the ~1500 human genes that remain uncharacterized? Happy to exchange ideas at my poster U-2 at #SWAT4LS 2023 Basel ! Human Proteome SIB Semantic Web

Check out Poster 12 @LS2Switzerland and talk to Paula Duek about the #neXtProt function prediction project for uncharacterized human proteins, and how to contribute! SIB Human Proteome

New release 2023-04-18 with > 3.75 million MS/MS peptides from PeptideAtlas and MassIVE ! SIB Human Proteome nextprot.org/news/new-relea…

Retrieve the 17453 PE1 entries that comply with the Human Proteome HPP data interpretation guidelines 3.0 in less than one second using our new SPARQL query nextprot.org/proteins/searc…

Did you know that about 1 in 4 neXtProt entries (5415 in total) are associated with a disease? 98 disease-associated proteins are encoded on chromosome 13. Find out how many are on your favorite chromosome using this SPARQL query: nextprot.org/proteins/searc… Human Proteome

Two years ago, neXtProt launched the community function prediction pages for uncharacterized proteins. Now, 239 entries have hypotheses. Check them out and help us reach the 500 entry mark! nextprot.org/proteins/searc… Human Proteome SIB Int Soc Biocuration Maxat Kulmanov Tunca Doğan

Many thanks to the organizers for this great opportunity to exchange fresh ideas on how to better characterize the human proteome in the frame of in the HPP Grand challenge! Charles Pineau Fernando Corrales Human Proteome

The Proceedings of SWAT4HCLS2023 have just been published! Our Data in use paper (ceur-ws.org/Vol-3415/paper…) describes query NXQ_00300, that highlights 44 uncharacterized human proteins potentially involved in brain function than can be studied in Drosophila melanogaster!

Poster presented at iMig2023 on the molecular pathway of Pleural Mesotelioma in WikiPathways, constructed by the community! The poster shows uses of the pathway for omics data interpretation, and integration with other databases such as neXtProt . doi.org/10.6084/m9.fig…

Congratulations to SIB’s @PascaleGaudet, recipient of the International Society for #Biocuration’s “Exceptional contribution to biocuration” award. A fantastic recognition of her work (incl. on @nextprot_news Gene Ontology @[email protected]) and #Swiss excellence in the field: biocuration.org/pascale-gaudet…

How can Next Generation Proteomics help us predict the functions of the ~1500 human genes that remain totally uncharacterized? Happy to exchange ideas with #BSPREUPA2023 attendees tomorrow at poster 146 ! SIB Human Proteome News@EuPA

Chi-Biotech and neXtProt joined their forces and are happy to deliver a mirror site of neXtProt in China, nextprot.cn, which should considerably improve the usability of neXtProt for all our users located in China and other Asian countries! SIB Human Proteome

Happy that neXtProt and its associated set of 140 SPARQL query examples could be used as benchmarks for this nice study on interoperability between biological and chemical databases ! ELIXIR Czech Republic SIB

The #VEP tool is now up-to-date with PolyPhen-2 and SIFT scores from Ensembl release 109 ! SIB nextprot.org/news/updated-v…

New release 2023-09-11 with updated subcellular localization and expression data from HPA version 23 ! SIB Human Proteome Human Protein Atlas nextprot.org/news/new-relea…

Happy to be at #HUPO2023 in Busan and discuss the last HPP metrics at the #BioinformaticsHub !

Don't miss the farewell lecture of SIB co-founder and Group Leader, Amos Bairoch (Amos Bairoch) at UNIGE_en on 28 September in which he will share insights from his remarkable career spanning 4 decades! 👉tinyurl.com/yhmp8amn #bioinformatics

Two weeks ago, I had the pleasure to present the neXtProt Function prediction project at #HUPO2023. Since then, predictions were added for 12 proteins. Now, 244/1521 uncharacterized proteins have hypotheses! shorturl.at/yEOZ9 Human Proteome SIB Int Soc Biocuration Charles Pineau

Happy that the neXtProt set of manually curated function predictions for 239 uncharacterized proteins could be used to evaluate DeepGO-SE, a new powerful AI-based protein function predictor developed by Maxat Kulmanov at KAUST! Full story here: nature.com/articles/s4225……… SIB

Ensuring the Future of neXtProt: Your ideas matter! Due to funding issues, neXtProt will cease operations by year-end. We are exploring new ways to repurpose or relocate its valuable components and need your creative ideas. Feel free to contact us! SIB Int Soc Biocuration Semantic Web