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I can only stress how much fun this fruitful collaboration was and still is. Thank you Shreejoy Tripathy and Derek Howard! Looking forward to hearing your comments #paincommunity #patchseq #ionchannel #pain #itch #microneurography #transcriptomics

Excited to share our single-cell study on aging mouse brain published in Nature today! We found an aging hotspot in specific hypothalamic cell types involved in energy homeostasis, which show both decreased neuronal function and increased immune responses. doi.org/10.1038/s41586…

that moment where you're asked to review a paper that you read in preprint form in a journal club almost 2 years ago but you don't remember anything about the paper. =\

Just had a meeting with a collaborator with an awesome NIMH program officer (PO) who provided super useful feedback on our grant. Why doesn't this exist in Canada within the CIHR system?

The results for schizophrenia were fascinating. The top results included cell types previously thought to contribute to schizophrenia (somatostatin and parvalbumin interneurons). Further, striatal neurons with high expression of the D2 dopamine receptor gene were also associated.

imo having a good success rate on grant applications (esp on 1st or 2nd submissions) is fairly correlated with getting good internal feedback on proposal drafts from colleagues / POs.

Liisa, thanks for being this up. It is not efficient to have the verification code last for one use. As mentioned 👇🏻. Yesterday's tally for verification codes was 8. Please consider the end user experience when implementing change to sites. CIHR

Devastating news from the NIH that will see a massive shrinkage of biomedical research in the US. If unchanged will shrink the number of Universities that meaningfully carry our research to those that can backfill unsupported research costs with philanthropy. The Canadian model.

🧬 Join our lab in Toronto, Canada 🇨🇦! Exciting postdoc opening at the intersection of machine learning and cancer genomics - developing next-gen models to predict genetic interactions with in-the-loop validation. Apply ➡️ apply.interfolio.com/162929 or DM for more details!

The Chamessian Lab WashU Pain Center is recruiting a #postdoctoral research associate to build on the foundational findings from our recent preprint showing that ion channels can be degraded by PROTACs. #TPD #PROTAC #drugdiscovery #pain #ionchannels. We're a fun group with an

The NIH website, and associated sites, are officially offline. Crucial bioinformatics tools like BLAST, ffq, gget depend on these services. This is completely unacceptable. #methodsmatter

Time for 🇨🇦 to Lead.

Exciting news! Apply now for the Single Cell Workshop 2025, June 19-20 at the Montreal Neurological Institute! Topics: sample prep, analysis workflows, data management, and open science. Free to attend, but spots are limited. Apply by April 25: lnkd.in/eErvbcRg.

Cell type-specific associations with Alzheimer's Disease conserved across racial and ethnic groups biorxiv.org/content/10.110…

What happens to all those alternative transcripts? 👉 Many are translated 👉 Proteolytic processing adds even more diversity Integrated mRNA & protein isoform landscape now out on bioRxiv! doi.org/10.1101/2025.0… #proteomics #transcriptomics #systemsbiology