Years before memory loss or hippocampal atrophy, Alzheimer’s disease begins in the neuromodulatory nuclei of the isodendritic core. To understand Alzheimer’s, we need to understand these systems. Our latest work get us closer to this goal. READ HERE 👀: rdcu.be/dJMzW

It’s wonderful to host Paul Yushkevich here at Amsterdam UMC. Today he gave a wonderful talk on ex-vivo postmortem imaging of hemispheres and the medial temporal lobe region, highlighting fantastic work on anatomical and neuropathological registrations 🤩 #collaborations

All ready for Philadelphia, just a few more days! #AAIC2024 Presentations ready ✅ Posters printed ✅ Team slide with overview ⬇️ See you there!

Lets get started! #AIC preconference at #AAIC2024 🥳

Faboulous presentation by Niels Reijner at the Atypical Alzheimer's Disease PIA at #AAIC24 on pathological correlates of MRI volume in typical and atypical AD phenotypes. 🤩🤩 Anatomy & Neurosciences Alzheimercentrum Amsterdam Amsterdam Neuroscience | Amsterdam UMC Amsterdam UMC

Important work on parcellating ex-vivo MRI images, useful as a bridge between regional neuropath data and parcellated in-vivo images.

Great and relevant talk with beautiful visuals! 🤩 #AAIC24 #doeidoei

Loved Greg Dunn Neuro Art at the Franklin institute, recognized it immediately! #AAIC2024

Biomarker and diagnostic approaches to LATE - excellent session! Love the translation from postmortem to in-vivo MRI data by Paul Yushkevich 🤩

Last but not least, team member Alex presenting her data on lower #amygdala and #hippocampus volume in #LATE; a postmortem MRI and neuropathology study. #AAIC2024 Alzheimercentrum Amsterdam

Off to a fantastic start at 8am on a Wednesday morning! Three talks on in-vivo MTL volume differences in different #FTD subtypes, on path hallmarks and #amygdala volume, and on 7T segmentation methods for quantitative analysis. #AAIC2024 Laura Wisse Pulkit Khandelwal

Fabulous talk by Baayla DC Boon, not on Abeta plaques, but on regional tangle count distribution, including the nucleus basalis of Meynert! #AAIC2024

Many thanks for the wonderful conference and Philadelphia experience! #AAIC24

Happy to be back in The City again! 🗽

New publication, "the neocortical infrastructure for language involves region-specific patterns of laminar gene expression" A collaboration with Clyde Francks and team! pnas.org/doi/10.1073/pn…

A nice thread with lots of anatomy resources!

First #Neuroscale team meeting after the summer, and rather than everyone talking about their holidays, we gave an update on how all our pets were doing. A goldfish, bunny, two cats, a dog, and horses. They’re all doing well and had a lovely summer.

In this study, the authors investigated whether neuropathologic processes contribute to brain regional topologic properties of integration and segregation and brain network resilience in #ParkinsonDisease: bit.ly/3WuQBD1 #NeuroTwitter