Bisphosphonates can be used in patients with CKD 1-3b and kidney tx. But, the main risks of bisphosphonate use in patients with advanced CKD or on dialysis include 1. More rapid GFR decline 2. Long-term effects within bone that may induce or exacerbate low turnover states.

#hypercalcemia itself can cause reversible #nephrogenicdiabetesinsipidus via induction of autophagic degradation of #aquaporin 2 channels

The differential for PTH-dependent #hypercalcemia includes 1⃣Primary hyperparathyroidism 2⃣Tertiary hyperparathyroidism 3⃣Familial hypocalciuric hypercalcemia 4⃣Lithium therapy

Hypertension in CKD: Pathophysiology from Faruk Turgut,MD #Nephpearls #IMPearls #PathophysiologyPearls 👉 link.springer.com/book/10.1007/9…

Approach to workup of ascites. Taught to me by Drs Terin Sytsma and Jason Szostek.

#Hypokalemia enhances ammoniagenesis in PT, ⬆️H secretion and HCO3 reabsorp. inPT, activates H/ATPase, Cl/HCO3 in A-interc.cells, induces the expression and activity of the nongastric H/KATPase in CD and ⬇️the expression of the HCO3 secreting transporter pendrin in B-interc.cells

How to interpret #hsTnT and #NTproBNP in patients with CKD.

#healthykidneyhealthylife

@ERAkindey education leaflet, how to lower #phosphate in #diet

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Novel strategies in nephrology: what to expect from the future? doi.org/10.1093/ckj/sf…

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Renin–Angiotensin System Inhibition in Advanced CKD | NEJM nejm.org/do/10.1056/NEJ…

#Magnesium is primarily an intracellular cation stored in bone, muscle, and soft tissue, with only 1% of #magnesium present in the extracellular fluid. Of this 1%, about ⅓ is plasma protein bound, and the remaining ⅔ is freely filtered through the kidney.

Currently, what we have for #CKD management.

Turkish Journal of Nephrology TürkNefrolojiDerneği

In a patient with resistant hypertension receiving ARB+CCB+diuretic on maximaly tolerated dose, which drug as the fourth-line agent would you prescribe to control BP?

Pseudohypercreatininemia; An interesting #case #AKI #creatinine

#uricacid #CKD #cardiovascularmortality

#RASinhibitors in patients with #CKD Recommendations from the #KDIGO guidelines