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Yun Chen of MechE Hopkins led this work in Nature Physics. How membrane ruffling senses solution viscosity. Biophysical modeling by Jian Liu of Cell Biology. Myong Hyun Jo provided cool data on single molecule tension sensor. nature.com/articles/s4156…

Here we show that neutrophils sense the level of fluid drag transduced through individual β2-integrin bonds, providing an intrinsic means to modulate inflammatory response in the microcirculation. mdpi.com/2073-4409/11/1…

Congratulations to Tim for winning the Lasker award!!!

Integrins: The receptors that keep it together youtu.be/4k60P3Pnh30 via YouTube

I like timelines a lot. Here's a timeline of 60 years of GFP discovery and engineering, made for FocalPlane: focalplane.biologists.com/2022/10/04/six…

And it’s online, I’m very proud to share that our paper on neutrophil transendothelial migration hotspots can be found online @EMBOreports! embopress.org/doi/full/10.15… Here is a short summary detailing our major findings: 1/9

Celebrating a small victory of the day. up next Brazil #KORPOR

The Cys-conjugated Cy dyes are always more prone to photobleaching than those labeled through amide bonds. Why? Working with Chunlai Chen's lab, we provide a simple solution to this issue. See our new paper on J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…

The Institute for Protein Innovation (IPI) introduces our recent work. Uncovering the secrets of mechanotransduction, one integrin receptor at a time proteininnovation.org/2023/03/integr…

TJ’s cutting-edge research “is based on the idea that DNA mutations can act directly through DNA physics, such as bendability and condensability.” Here, he shares what he calls ‘molecular fireworks’ 🎆. Learn more: pubs.acs.org/doi/10.1021/ac… 2/4

Determination of single-molecule loading rate during mechanotransduction in cell adhesion | Science science.org/doi/10.1126/sc…

Cells connect with their environment through surface receptors and use physical tension to regulate cellular processes. A new study develops an overstretching tension sensor to allow more accurate force measurement in physiological conditions. Taekjip Ha ow.ly/waEQ50R1Nvb

Research Highlight by Rita Strack : TJ Ha Taekjip Ha, Myung Hyun Jo, and colleagues develop a single-molecule method for probing loading rates in mechanical force measurements. Original paper: science.org/doi/10.1126/sc… Highlight: nature.com/articles/s4159…

Congratulations to the two GRS signaling by adhesion receptor best talk winners Milan Ruffini Collins and MyungHyun.Jo as well as GRS participants Margarida Dantas and @VignesHelene for giving fantastic talks at the GRC, too! Super impressive work by all of you! 🤩